An efficient synthesis and biological activity of substituted p-benzoquinones.

Bioorg Med Chem

Department of Pure and Applied Chemistry, Maharshi Dayanand Saraswati University, Ajmer 305 009, India.

Published: December 2006

An efficient synthesis of 2,5-diarylamino-3,6-dichloro-1,4-benzoquinone derivatives has been achieved by condensing mono substituted anilines with tetrachloro-p-benzoquinone in presence of fused sodium acetate as condensing agent under microwave irradiation without any solvent. All the synthesized compounds were tested for their antibacterial and antitumour activity using standard drugs.

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http://dx.doi.org/10.1016/j.bmc.2006.08.036DOI Listing

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