It is well established that Tourette syndrome has a neurobiologic origin. Although pharmacotherapy is the most commonly prescribed intervention, there is considerable evidence to support the use of behavior therapy, specifically habit reversal training, as an alternative or adjunct treatment for some individuals with Tourette syndrome. Unfortunately, many professionals are unfamiliar with habit reversal training. The purpose of this review is to provide readers with a brief review of empiric studies on habit reversal training, update readers on the current state and future of behavior therapy for Tourette syndrome, and provide resources for those readers interested in additional information.
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http://dx.doi.org/10.1177/08830738060210080101 | DOI Listing |
Sci Rep
January 2025
Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Jilin University, 1 Xinmin Street, Changchun City, Jilin Province, China.
Parkinson's disease (PD) is a complex neurodegenerative disorder influenced by both genetic and environmental factors, including dietary habits. Despite considerable research, the relationship between food intake and PD risk remains poorly understood. Here, we conducted a comprehensive Mendelian randomization analysis to investigate the association between a wide spectrum of food intake and PD risk.
View Article and Find Full Text PDFPrim Care Companion CNS Disord
January 2025
Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Subcell Biochem
January 2025
Department of Biology and Biotechnologies C. Darwin, Sapienza University of Rome, Rome, Italy.
Epigenetic mechanisms are key processes that constantly reshape genome activity carrying out physiological responses to environmental stimuli. Such mechanisms regulate gene activity without modifying the DNA sequence, providing real-time adaptation to changing environmental conditions. Both favorable and unfavorable lifestyles have been shown to influence body and brain by means of epigenetics, leaving marks on the genome that can either be rapidly reversed or persist in time and even be transmitted trans-generationally.
View Article and Find Full Text PDFJ Psychiatr Res
January 2025
Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, 52246, USA; Iowa Neuroscience Institute, University of Iowa, Iowa City, IA, 52246, USA; Yale Child Study Center, Yale School of Medicine, New Haven, CT, 06510, USA. Electronic address:
Prenatal stress is a risk factor for neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD). However, how early stress modification of brain development contributes to this pathophysiology is poorly understood. Ventral forebrain regions such as dorsal striatum are of particular interest: dorsal striatum modulates movement and cognition, is altered in NDDs, and has a primarily GABAergic population.
View Article and Find Full Text PDFPolymers (Basel)
December 2024
Engineering Research Center of Technical Textiles, Ministry of Education, College of Textiles, Donghua University, Shanghai 201620, China.
Smart fibers with tunable luminescence properties, as a new form of visual output, present the potential to revolutionize personal living habits in the future and are receiving more and more attention. However, a huge challenge of smart fibers as wearable materials is their stretching capability for seamless integration with the human body. Herein, stretchable thermochromic fluorescent fibers are prepared based on self-crystallinity phase change, using elastic polyurethane (PU) as the fiber matrix, to meet the dynamic requirements of the human body.
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