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Article Synopsis
  • - The paper investigates ocular circulation issues and electrical activity changes in a patient with CADASIL, characterized by various neuro-ophthalmic symptoms like transient vision loss, migraines, and diplopia.
  • - CADASIL diagnosis was confirmed through genetic testing for a mutation, immunohistochemistry showing specific material in blood vessels, and MRI revealing brain lesions and infarcts.
  • - Findings like decreased blood flow in retinal arteries and retinal changes suggest that transient vision loss may result from altered blood dynamics and vessel narrowing in the eye, supported by observed changes in electroretinogram amplitudes and imaging results.
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Coccidioidomycosis (CM), caused by the dimorphic fungi and , typically presents as acute or chronic pulmonary disease. However, disseminated disease occurs in about 1% of patients. Disseminated CM may affect multiple organ systems, including cutaneous, osteoarticular, and central nervous system sites.

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Macular Infarction following Intravitreal Clindamycin Injection : A Case Report.

J Curr Ophthalmol

October 2021

Eye Research Center, The Five Senses Institute, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.

Purpose: To report a case of retinochoroiditis that was complicated by macular infarction following intravitreal clindamycin injection.

Methods: A 32-year-old otherwise healthy woman with the diagnosis of reactivation of retinochoroiditis in her right eye, underwent intravitreal clindamycin injection. Shortly after injection, the visual acuity deteriorated, and the fundus examination revealed an extensive area of macular necrosis accompanied by vascular occlusion.

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Background: Ocular involvement in catastrophic antiphospholipid syndrome (CAPS), a rare, life-threatening form of antiphospholipid syndrome (APS) that results in multiorgan failure and a high mortality rate, has rarely been reported.

Case Presentation: A 15-year-old girl presented with sudden vision blurring in both eyes. She had marked optic disc swelling and macular exudates in the right eye and intra-arterial white plaques, a few retinal blot hemorrhages, and a white ischemic retina in the left eye.

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Purpose: To report a case of systemic and ocular toxoplasmosis in an immunocompetent patient, who developed myocarditis with resulting cardiogenic shock and multiple organ failure, followed by bilateral panuveitis masquerading as endogenous endophthalmitis.

Methods: Single case report with images.

Results: A 59-year-old man with a history of monoclonal gammopathy of undetermined significance and associated scleromyxedema but otherwise immunocompetent was admitted to the intensive care unit for cardiogenic shock and multiple organ failure due to presumed viral myocarditis.

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