Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1524-4725.2006.32264.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Simplified treatment of chronic scalp wounds with exposed skull.
Wounds
October 2024
Voorhees Surgery Center, Division of Plastic Surgery, Virtua Medical Center, Voorhees, NJ.
Background: Exposed cranial bone can present a considerable challenge to the reconstructive surgeon. Removal of the outer cortex of exposed skull bone has proven effective in the management of complex scalp wounds for which traditional reconstruction efforts were limited.
Objective: To demonstrate a simplified approach for management of scalp wounds with exposed skull.
A Sr@Ag-based spatiotemporal and step-release scaffold against chronic osteomyelitis, fabricated by coaxial 3D-printing.
Biomaterials
March 2025
Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing, 100084, People's Republic of China; Key Laboratory of Advanced Materials of Ministry of Education of China, School of Materials Science and Engineering, Tsinghua University, Beijing, 100084, People's Republic of China. Electronic address:
Chronic osteomyelitis (OM) represents a severe and persistent infectious bone disease. Effective treatment requires controlled anti-inflammatory releases and bone regeneration across disease phases. A Sr@Ag-based scaffold was successfully printed, featuring micron-scale coaxial fibers containing Ag-doped hydroxyapatite (HA) in the outer layer of PLLA and Sr-doped HA in the inner layer of PLLA, facilitating the spatiotemporal and sequential release of Ag and Sr ions during OM treatment.
View Article and Find Full Text PDFThe role of GpsB in cell morphogenesis.
mBio
March 2024
Instituto de Tecnologia Química e Biológica António Xavier, Universidade NOVA de Lisboa, Oeiras, Portugal.
Article Synopsis
- For years, scientists believed Gram-positive bacteria had no specialized machinery for elongation, but recent findings reveal they can elongate using a pair of proteins called SEDS and PBP during cell division.
- Researchers utilized the Nebraska Transposon Mutant Library to discover additional proteins, including GpsB, SsaA, and RodZ, that assist in the elongation process.
- GpsB specifically helps regulate the positioning of other penicillin-binding proteins (PBP2 and PBP4) at the cell division site, crucial for maintaining the correct shape and function of the bacteria, particularly important due to the rising threat of antibiotic-resistant infections.
A spatiotemporal drug release scaffold with antibiosis and bone regeneration for osteomyelitis.
J Adv Res
December 2023
Shenzhen University General Hospital, Shenzhen 518060, China; Department of Human Reproduction, The Third Affiliated Hospital of Shenzhen University, Shenzhen 518001, China. Electronic address:
Introduction: Scaffolds loaded with antibacterial agents and osteogenic drugs are considered essential tools for repairing bone defects caused by osteomyelitis. However, the simultaneous release of two drugs leads to premature osteogenesis and subsequent sequestrum formation in the pathological situation of unthorough antibiosis.
Objectives: In this study, a spatiotemporal drug-release polydopamine-functionalized mesoporous silicon nanoparticle (MSN) core/shell drug delivery system loaded with antibacterial silver (Ag) nanoparticles and osteogenic dexamethasone (Dex) was constructed and introduced into a poly-l-lactic acid (PLLA) scaffold for osteomyelitis therapy.
Outcomes of Open Fronto-Facial Resection for Fungal Osteomyelitis of Frontal Bone.
Rambam Maimonides Med J
October 2022
Department of Otolaryngology and Head Neck Surgery, All India Institute of Medical Sciences, Raipur, India.
Introduction: The second wave of coronavirus disease 2019 (COVID-19) led to the resurgence of opportunistic infections due to the injudicious use of steroids. Sinonasal mucormycosis was declared an epidemic in India during the pandemic. Mucormycosis was managed effectively by surgical debridement along with systemic amphotericin B.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!