The method used by the working group was an iterative process based upon a structured review of the relevant literature by a group of reporters. The review papers were circulated to the members of the group before the conference and formed the basis for subsequent discussions. Each paper was subject to detailed collective analysis and subsequently modified on the basis of the panel's discussions and referenced to additional relevant literature where appropriate. The group assessed the levels of evidence for the statements made in the supporting documentation and recognized that it was necessary to adopt a compromise between acceptance of the lowest level, resulting in the largest body of material, and the highest level, which, in some cases, produced little evidence. While this approach does not represent endorsement of lower evidence levels per se, it was designed to provide conclusions of clinical utility within the existing knowledge base. The consensus statements were prepared after a detailed consideration of the papers submitted to the workshop by the working group. The papers were scrutinized, amended and approved by the group. The basis of each paper is described in the section on 'search strategy' and defines the parameters within which the consensus statements were prepared.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1111/j.1600-0501.2006.01358.x | DOI Listing |
Vaccines (Basel)
September 2024
Department of Health Sciences, University of Florence, 50134 Florence, Italy.
Haematologica
August 2024
Antonino Trizzino, Simona Gobbi, Fraia Melchionda, Marco Zecca, Elena Mastrodicasa, Massimo Provenzi, Monica Cellini, Daniela Onofrillo, Marco Rabusin, Bernd Raffeiner, Rosamaria Mura, Vito Miraglia, Alessandra Tozzo.
Primary hemophagocytic lymphohistiocytosis (pHLH) is a severe, life-threatening hyperinflammatory syndrome caused by defects in genes of the granule-dependent cytotoxic pathway. Here we investigated the clinical presentation and outcome in a large cohort of 143 patients with pHLH diagnosed in the last 15 years and enrolled in the Italian registry. The median age at diagnosis was 12 months (interquartile range, 2-81), and 92 patients (64%) fulfilled the HLH-2004 criteria.
View Article and Find Full Text PDFDiving Hyperb Med
December 2023
Prepared by the Working Group «SAFETY» of the COST Action B14 «HYPERBARIC OXYGEN THERAPY» May 2004 - Update 2022.
J Fungi (Basel)
September 2023
Kashkin Research Institute of Medical Mycology; North-Western State Medical University Named after I.I. Mechnikov, 191015 Saint-Petersburg, Russia.
We studied the risk factors, etiology, clinical manifestations, and treatment outcomes of COVID-19-associated invasive candidiasis (COVID-IC) in adult patients admitted to six medical facilities in St. Petersburg. (November 2020-December 2022).
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!