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Innovative Approaches to Eczema Treatment: A Review of Fevipiprant and Its Potential as a New Therapeutic Agent.
Prostaglandins Other Lipid Mediat
December 2024
Faculty of Pharmacy, Integral University, Kursi Road, Lucknow 226026, UP., India.
Eczema is also known as atopic dermatitis, which goes on to affect the skin as a chronic inflammatory disease. It is associated with a constant feeling of scratchiness, erthyma and disruption of the natural skin barrier. Treatment provided at present may improve some of the symptoms, for instance use of corticosteroids or immunosuppressive agents, however, there is an overwhelming need for better focused and effective methods of treatment with minimal adverse effects.
View Article and Find Full Text PDFArtificial intelligence in pediatric allergy research.
Eur J Pediatr
December 2024
Krefting Research Centre, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Box 424, 405 30, Gothenburg, Sweden.
Unlabelled: Atopic dermatitis, food allergy, allergic rhinitis, and asthma are among the most common diseases in childhood. They are heterogeneous diseases, can co-exist in their development, and manifest complex associations with other disorders and environmental and hereditary factors. Elucidating these intricacies by identifying clinically distinguishable groups and actionable risk factors will allow for better understanding of the diseases, which will enhance clinical management and benefit society and affected individuals and families.
View Article and Find Full Text PDFReflectance Confocal Microscopy Can Help in Detecting Clinically Silent Mammary Paget's Disease.
Diagnostics (Basel)
December 2024
UOC of Dermatology, Policlinico Umberto I Hospital, Sapienza Medical School of Rome, 00161 Rome, Italy.
Early detection and comprehensive diagnostic approaches for breast cancer are essential for improving prognosis. When it comes to changes in the skin of the breast or the nipple-areola complex (NAC), particularly if they are unilateral, it is essential to be vigilant, as these changes could be an early sign of underlying malignancy or other pathologies. Primary breast malignancies, such as mammary Paget's disease (MPD), can manifest as erythema, scaling, or ulceration of the NAC, while secondary cutaneous metastases from other breast carcinomas may present as nodules, erythematous plaques, or inflammatory reactions.
View Article and Find Full Text PDFDermatological dichotomy: Atopic dermatitis or mycosis fungoides?
Asia Pac Allergy
December 2024
Allergy and Clinical Immunology Department, Coimbra University Hospital Centre, Coimbra, Portugal.
Article Synopsis
- Atopic dermatitis (AD) and mycosis fungoides (MF) can be difficult to distinguish because they exhibit similar symptoms like inflamed and itchy skin lesions.
- A case study of a 19-year-old male with a past AD history highlights the diagnostic confusion when he developed atypical eczema-like lesions that required advanced testing to confirm MF after initial misdiagnosis.
- The case underscores the importance of accurate and early diagnosis to differentiate between AD and MF, as MF requires specific treatments, and it encourages further research into shared mechanisms for improved patient care.
Eczema is a common yet serious inflammatory skin condition affecting millions of children in the United States. Dark skin and/or African-American ethnicity are risk factors for increased eczema severity, most likely due to systemic racism expressed as lower socioeconomic status, increased environmental toxin exposure, decreased access to adequate medical care, and infrequent implementation of early intervention practices. Skin-directed management of eczema for caregivers is critically important for improving clinical outcomes of children with eczema.
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