Herein we report our 7-year-experience of cardiopulmonary bypass. Between April 1, 1999, and December 31, 2005, 8685 children with congenital heart disease underwent cardiopulmonary bypass in Shanghai Children's Medical Center. The number of cases increased every year, and the number of patients younger than 1 year or weighing <10 kg also increased. Different bypass technology was adapted according to the operation. Roller pumps were used for most of the patients. Crystal cardioplegia (St. Thomas II) was used until blood cardioplegia was introduced in 2003. Ultrafiltrators were set up for infants weighing <10 kg. Mortality rates per year ranged from 1.81% to 3.70%. The most frequent complication was low cardiac output, about 12% in recent years. Arrhythmia, infection, and lung complications were the next three most frequent problems after surgery.
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http://dx.doi.org/10.1097/01.mat.0000237696.56192.5b | DOI Listing |
Eur Heart J Case Rep
January 2025
Department of Pediatric Cardiology, Saarland University Medical Center, Kirrberger Str., Building 9, D-66421 Homburg/Saar, Germany.
World J Pediatr Congenit Heart Surg
January 2025
Anaesthesiology, Critical Care and Pain Medicine, All India Institute of Medical Sciences - Guwahati, Guwahati, India.
We present a case of severe hypertriglyceridemia (HTG) in a 21-month old female undergoing cardiac surgery for a ventricular septal defect and subaortic membrane excision. During the operation, a milky white supernatant was observed in the cardiopulmonary bypass circuit, prompting immediate lipid profile testing that revealed elevated triglycerides. The management involved maintaining anticoagulation with heparin dose-response testing and ensuring oxygenator function by measuring blood gas analysis, lactate, and arterial line pressure.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Cardiovascular Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
It remains controversial as to which optimal cannulation strategy ought to be employed in surgery for type A aortic dissection (TAAD). The aim of this study was to make a comparison of the clinical outcomes between single and double arterial cannulation. From January 2018 to December 2022, 403 individuals with TAAD were recruited for the study and were divided into two groups based on the cannulation approach.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Anesthesia and Pain Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea.
Background: Monitoring core temperature is important for patients under anesthesia. Esophageal and pulmonary artery blood temperatures can be used for measuring core temperature during general anesthesia. However, these methods pose challenges, especially when the placement of an esophageal thermometer and pulmonary artery catheter (PAC) is either impractical or not the preferred approach.
View Article and Find Full Text PDFFront Cell Neurosci
December 2024
Department of Trauma Center, The First Affiliated Hospital of China Medical University, Shenyang, China.
Cardiopulmonary bypass (CPB) and deep hypothermic circulatory arrest (DHCA) are indispensable core techniques in cardiac surgery. Numerous studies have shown that cardiopulmonary bypass and deep hypothermic circulatory arrest are associated with the occurrence of neuroinflammation, accompanied by the activation of microglia. Microglia, as macrophages in the central nervous system, play an irreplaceable role in neuroinflammation.
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