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Risk factors and a prediction model of severe asparaginase-associated pancreatitis in children.
Ann Hematol
December 2024
Department of Gastroenterology, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, No. 1678 Dongfang Road, Shanghai, China.
We aimed to investigate whether early clinical indicators were associated with eventual disease severity, and to develop a predictive model for severe asparaginase-associated pancreatitis (AAP). Seventy-five acute lymphoblastic leukaemia (ALL) cases with AAP admitted to Shanghai Children's Medical Center from March 2013 to August 2023 were divided into non-severe (n = 44) and severe (n = 31) groups based on Atlanta diagnostic and AAP grading criteria. We compared essential information, asparaginase(ASP) dosage form, cumulative dose, clinical characteristics and laboratory tests between the groups.
View Article and Find Full Text PDFHaematological parameters and biochemical indices of African catfish () exposed to glyphosate-based herbicide (Force up) for 96 hours.
Front Toxicol
November 2024
Department of Veterinary Public Health and Preventive Medicine, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria.
Article Synopsis
- - The study investigates the toxic effects of glyphosate-based herbicides on aquatic animals, focusing on haematological and biochemical impacts after exposing fish to different herbicide concentrations.
- - Seventy-five adult fish were acclimatised, then divided into control and treatment groups, with varying glyphosate concentrations administered over a 96-hour period for blood analysis.
- - Results indicated complex changes in blood parameters, with some showing initial increases but ultimately decreasing with higher glyphosate levels, and only the platelet values showed statistically significant effects.
Gram-Negative Bloodstream Infections in a Medical Intensive Care Unit: Epidemiology, Antibiotic Susceptibilities, and Risk Factors for in-Hospital Death.
Infect Drug Resist
November 2024
Department of Nephrology, The Third Xiangya Hospital of Central South University, Changsha, People's Republic of China.
Purpose: Gram-negative bloodstream infection (GNBI) poses a serious threat to critically ill patients. This retrospective study aimed to uncover drug resistance of pathogens and the GNBI effect on in-hospital death and distinguish death risk factors in a medical intensive care unit (ICU).
Patients And Methods: A retrospective study of all GNBI patients in the medical ICU of the Third Xiangya Hospital over 9 nine years was conducted.
Background: Mixed evidence exists regarding stroke rates when comparing self-expanding valves (SEVs) to balloon-expandable valves (BEVs) in transcatheter aortic valve replacement (TAVR). This study investigates the debris captured by the SENTINEL cerebral protection system (CPS) during TAVR.
Methods: Seventy-five consecutive patients who underwent TAVR with CPS from March to December 2023 were recruited.
Evaluation of the Diversities in the Inflammatory Responses in Cats With Bacterial and Viral Infections.
Vet Med Sci
November 2024
Department of Physiology, Faculty of Veterinary Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Article Synopsis
- The study examines how cats respond to bacterial versus viral infections, focusing on the inflammatory responses that play a key role in managing these infections.
- It involved 75 cats divided into three groups: healthy controls, those with bacterial infections, and those with viral infections, analyzing various blood parameters.
- Findings indicated that while some inflammatory markers were similar, certain markers like TGF-β were lower in viral infections, and WBC count and IL-6 levels were higher in bacterial infections, highlighting distinct response patterns that could aid in treatment strategies for feline diseases.
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