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Primary Sjogren's Syndrome Presenting As Pleuritis and Pleural Effusion.
Cureus
December 2024
Pulmonary and Critical Care Medicine, Lenox Hill Hospital, New York, USA.
Sjogren's syndrome is an autoimmune condition characterized by infiltration of exocrine glands but, in rare cases, can have extraglandular involvement with pleural effusion being an exceedingly rare form. Here we present a case of Sjogren's pleuritis resulting in pleural effusion, a rare initial presentation for Sjogren's syndrome. A woman in her 20s presented to the emergency department after a recent hospitalization for pneumonia, pleural effusion, and pulmonary embolism.
View Article and Find Full Text PDFSjögren's disease and systemic lupus erythematosus overlap syndrome as distinct entity at crossroads of two autoimmune disorders: clinical characterisation from two Italian reference centres for both the diseases.
Clin Exp Rheumatol
December 2024
Division of Rheumatology, Azienda Sanitaria Universitaria del Friuli Centrale, Santa Maria della Misericordia Hospital, Udine; and Department of Medicine (DMED), University of Udine, Italy.
Objectives: To characterise the overlap syndrome between Sjögren's disease (SjD) and systemic lupus erythematosus (SLE).
Methods: Consecutive patients clinically defined as affected by SjD and SLE overlap syndrome (SjD-SLE), belonging to two Italian rheumatology centres were classified following the application of both the SjD and SLE classification criteria. Clinical, functional, ultrasound and histological data were compared with patients suffering from only SjD or SLE.
The clinical phenotype of isolated ocular or oral dryness in Sjögren's disease.
Clin Exp Rheumatol
December 2024
Pathophysiology Department, Athens School of Medicine, National and Kapodistrian University of Athens; Research Institute for Systemic Autoimmune Diseases, Athens; and Laboratory of Immunobiology, Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Greece.
Objectives: To assess if isolated mouth or eye dryness constitutes distinct clinical phenotypes in Sjögren's disease (SjD).
Methods: We analysed 1765 patients meeting the 2016 ACR-EULAR SjD criteria, followed up at four centres in Greece and Italy (Universities of Pisa, Italy, and Athens, Harokopion, and Ioannina, Greece). Patients with isolated mouth or eye dryness were identified and matched 1:2 with those experiencing both symptoms, according to age at SjD diagnosis, gender, and disease duration.
Biology, morphology and taxonomy of a snail-feeding leech from North Carolina, USA, provisionally identified as Helobdella lineata (Verrill, 1874) (Glossiphoniidae): First evidence for extra-oral digestion in the Hirudinea.
Zootaxa
May 2024
Medical Leech Museum; 2 Bryngwili Road; Hendy; Pontarddulais; Swansea SA4 0XT; UK.
Article Synopsis
- This study focuses on Helobdella lineata, a l eechnative to northeastern North Carolina, providing the first detailed description of the species over a twelve-year period.
- Researchers collected 404 specimens from various locations, observing significant variability in dorsal papillae and pigment patterns, which suggest adaptive camouflage rather than separate species.
- A key discovery is H. lineata's unique adaptation for feeding on snails, involving specialized salivary cells that enable extra-oral digestion before ingestion, marking a major evolutionary change in its feeding mechanism.
A Case Report of Recurrent Hypokalemic Quadriparesis in the Setting of Distal Renal Tubular Acidosis Preceding Typical Sicca Symptoms in Primary Sjögren's Syndrome.
Cureus
September 2024
Internal Medicine, Government Medical College, Nizamabad, IND.
Sjögren's syndrome (SS) is an autoimmune disorder with glandular and extra glandular manifestations. The extra glandular manifestations include renal symptoms, primarily tubulointerstitial nephritis (TIN), while the glandular component involves the lymphocytic infiltration of exocrine glands. We describe the case of a 28-year-old woman who experienced two bouts of sub-acute onset recurrent flaccid quadriparesis in four months.
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