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The association between discourse production and schizotypal personality traits.
Schizophr Res
August 2024
Alabama Life Research Institute, The University of Alabama, Tuscaloosa, AL, United States of America.
Discourse abnormalities are a prominent feature in schizophrenia spectrum disorders, including poor lexical diversity, and have been found to differentiate patients from healthy subjects. However, discourse processing in individuals with high schizotypal personality traits is less understood and is often overshadowed by research on clinical psychotic symptoms. In the present study, we examined schizotypal traits at a non-clinical threshold and their association with lexical diversity and discourse coherence using two automated Natural Language Processing (NLP) tools - Type-Token-Ratio (TTR) measures from the Tool for the Automatic Analysis of Lexical Diversity (TAALED) and discourse coherence using sentence-level average cosign similarity with FastText to assess sentence similarity.
View Article and Find Full Text PDFWhole-exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry.
Cancer Res Commun
September 2022
Tuskegee University, Center for Cancer Research, Tuskegee, Alabama.
Unlabelled: In this study, we used whole-exome sequencing of a cohort of 45 advanced-stage, treatment-naïve Nigerian (NG) primary prostate cancer tumors and 11 unmatched nontumor tissues to compare genomic mutations with African American (AA) and European American (EA) The Cancer Genome Atlas (TCGA) prostate cancer. NG samples were collected from six sites in central and southwest Nigeria. After whole-exome sequencing, samples were processed using GATK best practices.
View Article and Find Full Text PDFCharacterization of Electronic Health Record Documentation Shortcuts: Does the use of dotphrases increase efficiency in the Emergency Department?
AMIA Annu Symp Proc
April 2022
Hackensack University Medical Center, Hackensack, NJ.
The problem of clinical documentation burden is ever-growing. Electronic documentation tools such as "dotphrases" were invented to help with the documentation burden. Despite the ubiquity of these tools, they are understudied.
View Article and Find Full Text PDFVisible Signs of Concussion and Cognitive Screening in Community Sports.
J Neurotrauma
January 2022
Turner Institute for Brain and Mental Health, Monash University, Clayton Campus, Melbourne, Victoria, Australia.
Video surveillance and detection of players with visible signs of concussion by experienced medical staff facilitates rapid on-field screening of suspected concussion in professional sports. This method, however has not been validated in community sports where video footage is unavailable. This study aimed to explore the utility of visible signs of concussion to identify players with decrements in performance on concussion screening measures.
View Article and Find Full Text PDFWe describe how our institution responded when an interpreter who participated in the consent process involving an individual with limited English proficiency refused to cosign consent documents attesting that the individual enrolling in the study understood the consent information and that her consent to enroll was voluntary. In developing our approach, our institution took into account ethical tensions between the Belmont principles of respect for persons, beneficence, and justice that apply to the protection of research participants and the professional principles of beneficence, fidelity, and respect for the importance of culture that are outlined in ethical guidelines for medical interpreters.
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