The pathomorphological and virological study of peculiar features of parainfluenza infection caused by intranasal, aerosol and oral administration of the virus was carried out. The most marked lesions in the respiratory tract were observed in hamsters infected by the intranasal route, whereas with other routes of infection the intensity of lesions was minimal. Such differences in the pathomorphological manifestations of the process are most probably due to uneven distribution of the virus in the respiratory organs and to peculiar features of the immunological response of the animals.
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