Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1086/507314 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Update on HIV Chemoprevention.
Annu Rev Med
January 2025
University of California, Los Angeles (UCLA) Clinical AIDS Research and Education (CARE) Center, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA; email:
Despite rapid advances in the field of HIV prevention and treatment, unacceptably high global HIV incidence rates highlight the ongoing need for effective HIV prevention interventions for populations at risk for HIV acquisition. This article provides an updated review of the current data surrounding HIV prevention strategies, including treatment as prevention (TasP), preexposure prophylaxis (PrEP), and postexposure prophylaxis (PEP), as well as advances in sexually transmitted infection biomedical prevention. This review provides an overview of the multiple PrEP modalities that are available globally, such as oral PrEP, injectable cabotegravir, and the dapivirine vaginal ring, and describes their respective clinical trials, efficacies, and regulatory approvals.
View Article and Find Full Text PDFProtecting the most vulnerable: The urgent need to include HIV-exposed children in malaria chemoprevention strategies.
PLoS Med
December 2024
ISGlobal, Barcelona, Spain.
Raquel González and colleagues discuss the drugs available to HIV-exposed children to prevent malaria infection and the urgent need to evaluate alternative agents.
View Article and Find Full Text PDFExtended sequential intravenous and oral antimicrobial therapy improves cure rate in postoperative intracranial neurosurgical infections: a Spanish multicenter retrospective study.
BMC Infect Dis
November 2024
Infectious Diseases Section, Hospital de Galdakao-Usánsolo, Galdakao, Vizcaya, Spain.
Background: Postoperative intracranial neurosurgical infections (PINI) complicate < 5% neurosurgeries. Scarce attention was dedicated to the extension and characteristics of its antimicrobial management considering their high morbidity, not negligible mortality, delayed hospital stay and increased healthcare costs.
Methods: We analyzed retrospectively (2014-2023) 162 PINI from eight Spanish third-level academic hospitals.
molecular surveillance to inform the Mozambican National Malaria Control Programme strategy: protocol.
BMJ Open
November 2024
Centro de Investigação em Saúde de Manhiça (CISM), Manhiça, Mozambique
Introduction: Malaria molecular surveillance has the potential to generate information on biological threats that compromise the effectiveness of antimalarial interventions. This study aims to streamline surveillance activities to inform the new strategic plan of the Mozambican National Malaria Control Programme (2023-2030) for malaria control and elimination.
Methods And Analyses: This prospective genomic surveillance study aims to generate genetic data to monitor diagnostic failures due to deletions and molecular markers of antimalarial drug resistance, to characterise transmission sources and to inform the implementation of new antimalarial approaches to be introduced in Mozambique (chemoprevention and child malaria vaccination).
Perioperative antibiotic practices amongst otorhinolaryngologists (ear, nose and throat surgeons) in South Africa.
S Afr J Surg
October 2024
Division of Otorhinolaryngology, Department of Surgery, Faculty of Health Sciences, University of Cape Town, South Africa.
Background: The primary goal of perioperative antibiotics is to reduce the rate of surgical site infections (SSI); however, in certain surgical procedures, the use of perioperative antibiotics has been shown to have no impact on the rate of SSI. Inappropriate use of antimicrobials increases cost, potential side effects and further promotes antibiotic resistance. This study aims to provide insight into the adherence of South African otorhinolaryngologists to available evidence-based international guidelines.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!