Few studies to date have examined age-related changes in markers of immune status in healthy older individuals. The immune status of 93 healthy individuals aged 55-70 years was assessed by two- and three-color flow cytometry and biochemical analysis. There were significant age effects (p
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The role of socioeconomic factors in sex differences in intrinsic capacity among older adults: A cross-sectional study in Taiwan.
Prev Med Rep
November 2024
National Center for Geriatrics and Welfare Research, National Health Research Institutes, Yunlin, Taiwan.
Objectives: The World Health Organization's Integrated Care for Older People (ICOPE) framework launched in 2019 is used to assess the intrinsic capacity of older individuals. Older women may face greater socioeconomic disadvantages, which can impact their physical and mental well-being. Therefore, we examined sex differences in intrinsic capacity and the influence of socioeconomic status.
View Article and Find Full Text PDFIntroduction: Melanopsin is a photopigment with roles in mediating sleep and circadian-related processes, which are often disrupted in Alzheimer's disease (AD). Melanopsin also impacts cognition and synaptogenesis. This study investigated the associations between melanopsin genetic variants, sleep, and markers of brain health.
View Article and Find Full Text PDFThe effectiveness of real-life cognitive and physical interventions on cognitive functioning in healthy older adults: A systematic review of the effects of education and training duration.
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February 2025
Department of Psychiatry and Psychotherapy, Medical School and University Hospital, 11 Eberhard Karls University of Tübingen, Tübingen, Germany.
Physical and cognitive interventions are deemed the primary methods of improving cognitive functioning in healthy older adults. However, the effectiveness of these interventions is still debated. This systematic review, synthesised findings from the literature on four different types of interventions: physical activities, cognitive training, cognitive stimulation and a combined intervention.
View Article and Find Full Text PDFBrain Age Modeling and Cognitive Outcomes in Young Adults With and Without Sickle Cell Anemia.
JAMA Netw Open
January 2025
Department of Neurology, Washington University in St Louis School of Medicine, St Louis, Missouri.
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Comparative Analysis of Dental Treatment for Children With and Without Special Healthcare Needs at Academic Dental Hospitals in South Africa.
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SAMRC/Developmental Pathways for Health Research Unit, Department of Paediatrics, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Background: Children with special healthcare needs (CSHCN) experience higher unmet dental treatment needs than their healthy peers (NSHCN).
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