More than half of sciatic nerve palsies after primary total hip arthroplasties are unexplained. In 2 such cases, magnetic resonance imaging localized compressive injury between the ischial tuberosity and femoral insertion of the gluteus maximus. After these cases, we hypothesized that during limb positioning, the sciatic nerve is compressed by the gluteus maximus tendon. We present the magnetic resonance imaging findings from these 2 cases and compare the number of sciatic nerve palsies in patients with release of the gluteus maximus tendon to patients without release during primary total hip arthroplasty. There were no cases of sciatic nerve palsy when the gluteus maximus was released, compared with 3 cases in the control group.
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http://dx.doi.org/10.1016/j.arth.2005.08.008 | DOI Listing |
Arthrosc Tech
December 2024
American Hip Institute Research Foundation, Chicago, Illinois, U.S.A.
Piriformis syndrome (PS) is an underdiagnosed condition, caused by entrapment of the sciatic nerve by the piriformis muscle tendon and adhesions in the deep gluteal space. We present a step-by-step endoscopic technique with the patient in a prone position through a posterior approach. This approach provides improved orientation for tracking the sciatic nerve from distal to proximal, facilitating the release of all adhesions and concluding with a piriformis tendon release.
View Article and Find Full Text PDFMuscle Nerve
January 2025
Division of Plastic Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.
Introduction: Motor recovery following nerve injury is dependent on time required for muscle reinnervation. This process is imperfect, however, and recovery is often incomplete. At the neuromuscular junction (NMJ), macrophage signaling aids muscle reinnervation.
View Article and Find Full Text PDFSmall Methods
January 2025
Department of Electrical and Computer Engineering, Sungkyunkwan University, Suwon, 16419, Republic of Korea.
Recently, implantable devices for treating peripheral nerve disorders have demonstrated significant potential as neuroprosthetics for diagnostics and electrical stimulation. However, the mechanical mismatch between these devices and nerves frequently results in tissue damage and performance degradation. Although advances are made in stretchable electrodes, challenges, including complex patterning techniques and unstable performance, persist.
View Article and Find Full Text PDFZhongguo Zhen Jiu
January 2025
College of TCM, Chongqing Medical University, Chongqing Key Laboratory of TCM for Prevention and Treatment of Metabolic Diseases, Chongqing 410007, China.
Objective: To assess the impacts of electroacupuncture (EA) on the gait, oxidative stress, inflammatory reaction, and protein degradation in the rats of denervated skeletal muscle atrophy, and explore the potential mechanism of EA for alleviating denervated skeletal muscle atrophy.
Methods: Forty male SD rats, 8 weeks old, were randomly assigned to a sham-surgery group, a model group, an EA group, and a p38 MAPK inhibitor group, with 10 rats in each group. The right sciatic nerve was transected to establish a rat model of denervated skeletal muscle atrophy in the model group, the EA group and the p38 MAPK inhibitor group.
J Physiol
January 2025
Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
We previously reported that elevated expression of phospholipid hydroperoxide glutathione peroxidase 4, an enzyme that regulates membrane lipid hydroperoxides, can mitigate sarcopenia in mice. However, it is still unknown whether a pharmacological intervention designed to modulate lipid hydroperoxides might be an effective strategy to reduce sarcopenia in aged mice. Here we asked whether a newly developed compound, CMD-35647 (CMD), can reduce muscle atrophy induced by sciatic nerve transection.
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