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Associations of Central Arterial Stiffness With Brain White Matter Integrity and Gray Matter Volume in MRI Across the Adult Lifespan.
J Magn Reson Imaging
January 2025
Department of Neurology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Background: Central arterial stiffening is associated with brain white matter (WM) damage and gray matter (GM) volume loss in older adults, but little is known about this association from an adult lifespan perspective.
Purpose: To investigate the associations of central arterial stiffness with WM microstructural organization, WM lesion load, cortical thickness, and GM volume in healthy adults across the lifespan.
Study Type: This is a cross-sectional study.
The relative associations of aortic and carotid artery stiffness with CeVD and cognition.
J Cereb Blood Flow Metab
September 2024
Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Article Synopsis
- A study involving 272 memory clinic participants aimed to explore the relationship between stiffness in aortic and carotid arteries and various aspects of cerebrovascular disease, cognition, and dementia subtypes.
- Researchers used applanation tonometry and carotid ultrasonography to measure artery stiffness and assessed cognitive function through tests like MMSE and MoCA.
- Results indicated that carotid artery stiffness was significantly linked to markers of cerebrovascular disease and cognitive impairment, showing a stronger impact than aortic stiffness on these health issues.
Simulation techniques in optometric education: Is a model eye for tonometry a valuable instruction tool?
Ophthalmic Physiol Opt
November 2024
Centre for Vision across the Lifespan (CVLS), The University of Huddersfield, Huddersfield, UK.
Purpose: Simulation techniques are used in healthcare education to support the development of clinical skills. The aim of this study was to investigate the perceived value of a tonometry model eye (TME) when used in teaching and learning the clinical skill of Goldmann applanation tonometry (GAT) in optometric education in the UK.
Methods: A retrospective two-armed cross-sectional study was conducted to investigate the perceived value of using a model eye for teaching and learning GAT in optometric education.
Performance of home-based self-tonometry (iCare HOME (TA022)) for measuring intraocular pressure among healthy and glaucoma patients.
F1000Res
June 2024
Department of Optometry, Manipal College of Health Professions (MCHP), Manipal Academy of Higher Education (MAHE), Manipal, Udupi (Dist), Karnataka, 576104, India.
The purpose of this study was to compare iCare HOME (TA022) with Goldmann applanation tonometer and to evaluate the self-tonometry measurements among the Indian population. Eligible patients underwent iCare HOME training through guided demonstration (verbal, pictorial, video) and practised self-tonometry measures using iCare HOME. Certification for independent iCare HOME measure was provided if first iCare HOME intraocular pressure (IOP) measurement fell within ± 5 mmHg of Goldmann applanation tonometer (GAT) measurement which was measured by the trained clinician (principal investigator).
View Article and Find Full Text PDFPreliminary Study on Pulse Wave Changes in Patients with Inflammatory Arthropathies Treated with bDMARDs.
J Clin Med
May 2024
UCO Medicina Clinica, ASUGI, Cattinara Teaching Hospital, Strada di Fiume 447, 34149 Trieste, Italy.
Patients with inflammatory arthropathies exhibit an increased cardiovascular disease (CVD) risk as compared to the general population, which is not fully quantified by the conventional CVD risk scores. Biotechnological disease-modifying drugs (bDMARDs) have proved beneficial to reduce the overall CVD risk in these patients, although CVD remains a major cause of increased mortality. Since it has been shown that pulse wave parameters and in particular carotid-femoral pulse wave velocity (cfPWV) are predictors of CVD risk, the aim of this study was to evaluate their changes in patients with inflammatory arthropathies before and after bDMARD therapy.
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