A new sesquiterpene-lactone (nubenolide) belonging to the guaianolide class along with its acetate (nubenolide acetate) and a dimer (bisnubenolide) have been isolated from Salvia nubicola collected from Quetta, Pakistan. Structures of all three new metabolites were elucidated with the aid of spectroscopic techniques including 2D-NMR. However, the structure of nubenolide was finally confirmed via single-crystal X-ray diffraction method.
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| http://dx.doi.org/10.1248/cpb.54.1235 | DOI Listing |
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