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Endoscopic ultrasonography-guided transesophageal pericardiocentesis was performed for a posteriorly located effusion not amenable to transthoracic drainage in a 58-year-old woman with a history of recurrent breast adenocarcinoma who presented with dyspnea. The patient had a pericardial effusion that resulted in cardiac tamponade. Transthoracic pericardiocentesis was unsuitable because of the posterior location of the effusion.

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Endoscopic ultrasonography-guided fine needle aspiration (EUS-FNA) is considered to be a highly beneficial and safe diagnostic tool. EUS-FNA now has a greater clinical impact because the technique is currently being applied for therapeutic as well as diagnostic purposes. The treatment of intra-peritoneal abscess after peptic ulcer perforation has traditionally been by surgery, especially when percutaneous abscess drainage is unfeasible.

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EUS-Guided Biliary Drainage.

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September 2010

Department of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan.

Endoscopic ultrasonography (EUS) combines endoscopy and intraluminal ultrasonography, and allows imaging with a high-frequency transducer over a short distance to generate high-resolution ultrasonographic images. EUS is now a widely accepted modality for diagnosing pancreatobiliary diseases. EUS-guided fine-needle aspiration (EUS-FNA) using a curved linear-array echoendoscope was initially described more than 20 years ago, and since then many researchers have expanded its indications to sample diverse lesions and have also used it for various therapeutic purposes.

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Objective: To study the efficacy and safety of endoscopic ultrasonography-guided fine-needle aspiration in the management of mediastinal diseases in Hong Kong.

Design: Retrospective review of prospectively collected data.

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Sarcoidosis is a multi-organ disorder of unknown etiology characterized by noncaseating epithelioid cell granulomas. The specimen for histopathological diagnosis is usually obtained by transbronchial lung biopsy (TBLB), but the diagnostic accuracy rate of TBLB is not satisfactory, especially for stage I patients. Since hilar and mediastinal lymphadenopathy is a common finding in patients with sarcoidosis, an approach to lymph nodes is expected to have a good diagnosis yield.

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