The purpose of the present study was to assess the in vitro activity of daptomycin against a well-defined collection of methicillin-resistant Staphylococcus aureus (MRSA) isolates (n = 98), including heterogeneously glycopeptide-resistant MRSA (hGISA) strains. Susceptibility testing was performed by using the Etest system. Daptomycin was potent against both glycopeptide-susceptible and hGISA strains.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1563506PMC
http://dx.doi.org/10.1128/AAC.00526-06DOI Listing

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