AI Article Synopsis
- The study aimed to examine how effective wireless capsule endoscopy (WCE) is at identifying small bowel issues in patients with chronic renal failure (CRF) experiencing obscure bleeding.
- Researchers compared 17 CRF patients with obscure bleeding to 51 patients with normal kidney function, finding that a higher percentage of CRF patients had positive small bowel findings (70.6% vs. 41.2%).
- The results indicated that small bowel angiodysplasia was more common in CRF patients, suggesting that WCE should be integrated into diagnostic procedures for these patients to help guide treatment options.
Article Abstract
Aim: To investigate the role of wireless capsule endoscopy (WCE) in detection of small bowel (SB) pathology in patients with chronic renal failure (CRF) and obscure bleeding.
Methods: Consecutive CRF patients with obscure bleeding were prospectively studied. Patients with normal renal function and obscure bleeding, investigated during the same period with WCE, were used for the interpretation of results.
Results: Seventeen CRF patients (11 overt, 6 occult bleeding) and 51 patients (33 overt, 18 occult bleeding) with normal renal function were enrolled in this study. Positive SB findings were detected in 70.6% of CRF patients and in 41.2% of non-CRF patients (P < 0.05). SB angiodysplasia was identified in 47% of CRF patients and in 17.6% of non-CRF patients. Univariate logistic regression revealed CRF as a significant predictive factor for angiodysplasia (P < 0.05). Therapeutic measures were undertaken in 66% of the patients with the positive findings.
Conclusion: According to our preliminary results, SB angiodysplasia was found in an increased prevalence among CRF patients with obscure bleeding. WCE is useful in diagnosis of gastrointestinal pathologies and in planning appropriate therapeutic intervention and, therefore, should be included in the work-up of this group of patients.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4088016 | PMC |
| http://dx.doi.org/10.3748/wjg.v12.i32.5182 | DOI Listing |
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