Ectasia after laser in situ keratomileusis.

Curr Opin Ophthalmol

Ophthalmology Research, Cedars-Sinai Medical Center and Department of Ophthalmology, UCLA School of Medicine, Los Angeles, California 90048, USA.

Published: October 2006

Purpose Of Review: The potential for litigation has resulted in increased interest in ectasia after laser in situ keratomileusis. This article summarizes papers written during this past year on this subject.

Recent Findings: A panel of refractive surgery experts have summarized the current state of knowledge on this subject and provided guidelines to minimize risk. Because ectasia may occur in the absence of risk factors, there may be corneas with biomechanical factors not detectable with present technology which are at risk. Several articles point out the limitations of the Orbscan (Bausch & Lomb, Rochester, New York, USA), in particular its accuracy and reproducibility with regard to data generated from the posterior surface of the cornea. A biomechanical model of the cornea is proposed which suggests that each cornea's response to laser in situ keratomileusis is unique. Several case reports are also reviewed which provide insight into pathogenesis and potential new treatment options; these include reports on histopathology, topographic pseudokeratectasia, ectasia from transient raised intraocular pressure, poor response to laser in situ keratomileusis after incisional surgery, intracorneal rings, collagen cross-linking and conductive keratoplasty to stabilize and sphericize the cornea with ectasia.

Summary: Our knowledge about ectasia is still in evolution. Insights into the biomechanics and genetics of the cornea may allow us to further reduce its occurrence.

Download full-text PDF

Source
http://dx.doi.org/10.1097/01.icu.0000243015.51886.3aDOI Listing

Publication Analysis

Top Keywords

laser situ
16
situ keratomileusis
16
ectasia laser
8
response laser
8
ectasia
5
situ
4
keratomileusis
4
keratomileusis purpose
4
purpose review
4
review potential
4

Similar Publications

Rapid validation of newly predicted materials through autonomous synthesis requires real-time adaptive control methods that exploit physics knowledge, a capability that is lacking in most systems. Here, we demonstrate an approach to enable real-time control of thin film synthesis by combining optical diagnostics with a Bayesian state estimation method. We developed a physical model for film growth and applied the direct filter (DF) method for real-time estimation of nucleation and growth rates during pulsed laser deposition (PLD).

View Article and Find Full Text PDF

Revisiting the female germline cell development.

Front Plant Sci

January 2025

College of Life Sciences, Fujian Provincial Key Laboratory of Haixia Applied Plant Systems Biology, State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, China.

The formation of the female germline is the fundamental process in most flowering plants' sexual reproduction. In , only one somatic cell obtains the female germline fate, and this process is regulated by different pathways. Megaspore mother cell (MMC) is the first female germline, and understanding MMC development is essential for comprehending the complex mechanisms of plant reproduction processes.

View Article and Find Full Text PDF

Laser absorption spectroscopy (LAS) is a well-established measurement technique for quantitative chemical speciation in a combustion environment. However, LAS measurement of nitric oxide (NO) in ammonia flames has never been reported in the literature. This is despite the community's recent strong interest in carbon-neutral ammonia combustion and the associated NO formation problem.

View Article and Find Full Text PDF

A dual pulse retrieval algorithm is introduced that builds upon time-domain interferometric strong-field ionization to simultaneously reconstruct both involved laser pulses in a waveform-resolved manner. The pulse characterization scheme removes many restrictions posed by former methods, leaving the avoidance of resonant ionization as a single boundary. It is widely and easily applicable at low cost and effort for common attosecond beamlines and allows for the robust and accurate in-situ retrieval of two unknown laser fields.

View Article and Find Full Text PDF

The development of high-brightness electron sources is critical to state-of-the-art electron accelerator applications like X-ray free electron laser (XFEL) and ultra-fast electron microscopy. Cesium telluride is chosen as the electron source material for multiple cutting-edge XFEL facilities worldwide. This manuscript presents the first demonstration of the growth of highly crystalized and epitaxial cesium telluride thin films on 4H-SiC and graphene/4H-SiC substrates with ultrasmooth film surfaces.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!