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Hydraulic Properties of a Rock-Soil-Root System: Insights From Fraxinus ornus L. Saplings Growing on Different Carbonate Rocks.
Plant Cell Environ
January 2025
Dipartimento di Scienze della Vita, Università di Trieste, Trieste, Italia.
Drought impacts trees in varied temporal and spatial patterns, suggesting that heterogeneity of below-ground water stores influences the fate of trees under water stress. Karst ecosystems rely on shallow soil overlying bedrock that can store available water in primary pores. A contribution of rock moisture to tree water status has been previously demonstrated, but actual mechanisms and rates of rock-to-root water delivery remain unknown.
View Article and Find Full Text PDFAntimicrobial peptide LL37 is potent against non-growing cells despite a slower action rate.
mSphere
December 2024
Department of Physics and Astronomy, California State University, Northridge, California, USA.
Unlabelled: Antimicrobial peptides (AMPs) have long been considered as potential agents against non-growing, dormant cells due to their membrane-targeted action, which is largely independent of the cell's growth state. However, the relationship between the action of AMPs and the physiological state of their target cells has been unclear, with recent reports offering conflicting views on the efficacy of AMPs against bacteria in a stationary phase. In this study, we employ single-cell approaches combined with population-level experiments to examine the action of human LL37 peptides against cells in different growth phases.
View Article and Find Full Text PDFThe growing concerns about the adverse impacts of light pollution on astronomy, the environment, biodiversity, human health, and energy use have brought increased attention to the issue on legal and political agendas. Various international frameworks and governments at different levels have taken action to mitigate the impacts of nighttime lighting. This article provides an overview of regulatory instruments adopted to protect the nocturnal environment, explaining triggers for regulatory changes, using an interdisciplinary perspective.
View Article and Find Full Text PDFNitazene opioids and the heart: Identification of a cardiac ion channel target for illicit nitazene opioids.
J Mol Cell Cardiol Plus
December 2024
School of Physiology, Pharmacology and Neuroscience, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
The growing use of nitazene synthetic opioids heralds a new phase of the opioid crisis. However, limited information exists on the toxic effects of these drugs, aside from a propensity for respiratory depression. With restricted research availability of nitazenes, we used machine-learning-based tools to evaluate five nitazene compounds' interaction potential with the hERG potassium channel, a key drug antitarget in the heart.
View Article and Find Full Text PDFSmall-angle rigid-unit modes requiring linear strain compensation.
Acta Crystallogr A Found Adv
January 2025
Department of Physics and Astronomy, Brigham Young University, Provo, Utah 84602, USA.
Group-theoretical and linear-algebraic methods and tools have recently been developed that aim to exhaustively identify the small-angle rotational rigid-unit modes (RUMs) of a given framework material. But in their current form, they fail to detect RUMs that require a compensating lattice strain which grows linearly with the amplitude of the rigid-unit rotations. Here, we present a systematic approach to including linear strain compensation within the linear-algebraic RUM-search method, so that any geometrically possible small-angle RUM can be detected.
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