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Influenza A Virus H7 nanobody recognizes a conserved immunodominant epitope on hemagglutinin head and confers heterosubtypic protection.
Nat Commun
January 2025
Department of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
Influenza remains a persistent global health challenge, largely due to the virus' continuous antigenic drift and occasional shift, which impede the development of a universal vaccine. To address this, the identification of broadly neutralizing antibodies and their epitopes is crucial. Nanobodies, with their unique characteristics and binding capacity, offer a promising avenue to identify such epitopes.
View Article and Find Full Text PDFContact Allergy to Methacrylate Containing Nail Products: Lack of Impact of EU Legislation. An Audit on Behalf of the European Environmental Contact Dermatitis Research Group (EECDRG).
Contact Dermatitis
December 2024
Department of Occupational and Environmental Dermatology, Lund University, Skåne University Hospital, Malmö, Sweden.
Background: There is a current fashion for the use of methacrylate-containing nail cosmetics that can induce allergic contact dermatitis. European Union (EU) legislation was introduced in 2021 that had the aim of preventing its development.
Objectives: To assess prevalence and exposures causing contact allergy to 2-hydroxyethyl methacrylate (HEMA) prior to and following implementation of the legislation.
Solid-state self carbo-passivation for refurbishing colloidal dispersity of catalytic silica nanoreactors.
Mater Horiz
December 2024
Creative Research Initiative Center for Nanospace-confined Chemical Reactions (NCCR), Pohang University of Science and Technology (POSTECH), Pohang 37673, Korea.
Silica-based nanostructures are among the most utilized materials. However, a persistent challenge is their irreversible agglomeration upon drying and heat treatments, restricting their homogeneous colloidal re-dispersion - a mandatory requirement for diverse bio-applications. We address this bottleneck by developing a self carbo-passivation (SCP) strategy: silica nanoparticles (NPs), pre-included with the catalytic metal precursors and organosilanes undergo thermochemical conversion with highly controlled interior-to-surface segregation of nanometer-scale "carbonaceous skin patches".
View Article and Find Full Text PDFPrevalence, pattern, contact sensitisers and impact on quality-of-life of occupational dermatitis among beekeepers in North India.
Contact Dermatitis
November 2024
Department of Dermatology, Venereology and Leprosy, Government Medical College Srinagar, University of Kashmir, Srinagar, Jammu and Kashmir, India.
Article Synopsis
- * Conducted over 18 months, the study involving 340 beekeepers found a 17.1% prevalence of dermatitis, primarily affecting hands, with significant links to how long individuals have been beekeeping and prior allergy history.
- * Although dermatitis is common among beekeepers, the overall effect on their quality of life is relatively minor, with propolis identified as a key allergen in the region.
Insights into hair dye use and self-reported adverse skin reactions in the Dutch general population: A cross-sectional questionnaire-based study.
Contact Dermatitis
October 2024
Department of Dermatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Article Synopsis
- - The study aimed to assess hair dye usage and self-reported skin reactions among the Dutch population, finding that 63.1% of participants used hair dye and 6.8% reported adverse reactions.
- - The research highlighted a positive link between hair dye users and various factors such as female gender, middle age, positive patch test results, and professions like hairdressing.
- - Findings indicated that adverse reactions were commonly mild and more likely in individuals with prior henna tattoo experiences, particularly in females, suggesting a need for increased awareness about hair dye safety.
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