AI Article Synopsis
- This study presents the first documented case of autoimmune thyroid encephalopathy resulting in multifocal motor status epilepticus in a 37-year-old woman.
- The patient exhibited severe symptoms, including intractable multifocal seizures and asymmetrical quadriparesis, with MRI revealing abnormal signals in the precentral cortices.
- After diagnosing autoimmune thyroiditis through thyroid examinations and function tests, the patient's seizures stopped following intravenous steroid treatment, suggesting the need for screening anti-thyroid antibodies in similar seizure cases.
Article Abstract
We report the first case of an autoimmune thyroid encephalopathy presenting with multifocal motor status epilepticus. A 37-year-old female patient was admitted with multifocal motor seizures intractable to intravenous status epilepticus treatments, asymmetrical quadriparesis, truncal ataxia and continuous semi-rhythmical jerks. Pathological signal alterations were detected in both precentral cortices in MRI examination. Autoimmune thyroiditis was diagnosed after radiological examinations of the thyroid gland and thyroid function tests. Seizures promptly ceased following intravenous steroid treatment. Immunohistochemistry studies showed mild to moderate neuronal staining with the plasma and CSF samples. Remarkably, autoimmune thyroiditis may present with migrating focal motor status epilepticus. We recommend anti-thyroid antibody screening for multifocal motor status epilepticus cases of unspecified cause.
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| http://dx.doi.org/10.1177/155005940603700308 | DOI Listing |
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