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3D bioprinted dynamic bioactive living construct enhances mechanotransduction-assisted rapid neural network self-organization for spinal cord injury repair.

Bioact Mater

April 2025

State Key Laboratory of New Ceramics and Fine Processing, Key Laboratory of Advanced Materials, School of Materials Science and Engineering, Tsinghua University, Beijing, 100084, China.

Biomimetic neural substitutes, constructed through the bottom-up assembly of cell-matrix modulus via 3D bioprinting, hold great promise for neural regeneration. However, achieving precise control over the fate of neural stem cells (NSCs) to ensure biological functionality remains challenging. Cell behaviors are closely linked to cellular dynamics and cell-matrix mechanotransduction within a 3D microenvironment.

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Aim: To identify existing public knowledge regarding diabetes and diabetes-related services offered to persons living with diabetes in the City of Malmö.

Methods: A literature review of City of Malmö's website, public statistics, School health documentation, job databases, education programs, local newspaper, Swedish National Diabetes Register, and was performed in 2020.

Results: We identified political decisions about diabetes nurses in home care, financing a project about diabetes complications, and funding support in schools for designated children.

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Objectives: This study aims to investigate whether social networks and physical exercise mediate the relationship between new and constant use of intelligent virtual assistants (IVAs) and cognitive function in older adults in China and explore the potential differences across living arrangements and education levels.

Methods: This study utilized nationally representative longitudinal data from 2018 to 2020, including a sample of 8343 older adults aged 60-80. A path-analytic model was employed to examine the relationship between IVAs use and cognitive function, as well as the mediating roles of social networks and physical exercise.

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The most common carcinoma-related cause of death among women is breast cancer. Early detection is crucial, and the manual screening method may lead to a delayed diagnosis, which would delay treatment and put lives at risk. Mammography imaging is advised for routine screening to diagnose breast cancer at an early stage.

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Objectives: Prior studies suggested that urinary incontinence (UI) may be a risk factor for nursing home (NH) placement among older community-dwelling individuals. Our objectives were to evaluate if UI is an independent risk factor in NH placement among assisted living (AL) residents and assess the impact of UI on NH placement by race/ethnicity.

Design: This retrospective cohort study is based on the 2019-2021 Medicare enrollment and claims data.

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