Background And Objectives: In intravenous access to veins there is a risk of puncturing venous valves or blocking of the catheter by the valves. Therefore, we have investigated whether and how photoacoustic imaging (PAI), which visualizes the lumen of blood vessels, can be used to detect these valves.
Study Design/materials And Methods: Venous valves in superficial veins on the dorsal side of the hand of human volunteers were located by palpation and visual inspection. Next, this location was imaged using PAI.
Results: In 16 of 21 human volunteers venous valves that were found by palpation could be observed by PAI as local discontinuities in the imaged vessel. From these images, four characteristic features by which venous valves can be recognized in photoacoustic images were identified.
Conclusions: PAI has the potential to be applied in the detection of venous valves.
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http://dx.doi.org/10.1002/lsm.20390 | DOI Listing |
Comput Methods Programs Biomed
December 2024
College of Mechanical and Electrical Engineering, Wenzhou University, Wenzhou, 325035, China.
Background And Objective: Deep vein thrombosis (DVT) of the lower limbs is a critical global vascular disease. Accurately assessing and predicting the efficacy of DVT treatment remains a significant challenge due to a lack of understanding of the mechanisms by which the level of patient-specific embolization and the rate of drug injection affect thrombolytic therapy.
Methods: In this study, we used the computed tomographic venography (CTV) clinical method to obtain patient-specific parameters, and the flow-solid interaction (FSI) method combined with biochemical response modeling of thrombolysis to analyze patient-specific hemodynamic and biomechanical characteristics and to quantitatively assess the effects of three vessel embolism levels (VEL) versus two drug injection rates (DIR) on bifurcated femoral venous thrombolytic therapy.
JPRAS Open
March 2025
Reconstructive Surgery and Regenerative Medicine Research Centre, Institute of Life Sciences, Swansea University Medical School, Swansea, United Kingdom.
Understanding the vascular anatomy of the face is crucial for ensuring safe clinical practices, especially as aesthetic procedures involving hyaluronic acid fillers are gaining popularity. Although vascular complications from these procedures are rare, there has been a documented increase in adverse events linked to venous and arterial occlusions. This review addresses the knowledge gap regarding the facial venous system compared to the well-documented facial artery system, emphasising the importance of thorough anatomical knowledge to mitigate risks during injectable cosmetic procedures.
View Article and Find Full Text PDFComput Biol Med
December 2024
Research Center for Mathematics and Interdisciplinary Sciences, Shandong University, Qingdao, 266237, China; Frontiers Science Center for Nonlinear Expectations, Ministry of Education, Qingdao, 266237, China. Electronic address:
Research on venous hemodynamics is pivotal for unravelling venous diseases, including varicose veins and deep vein thrombosis, essential for clinical management, treatment and artificial valve design. In this study, a three-dimensional (3D) numerical simulation, employing the immersed boundary/finite element method, is constructed to explore the fluid-structure interaction (FSI) between intravenous blood and venous valves. A hyperelastic constitutive model is used to capture the incompressible, nonlinear mechanical response.
View Article and Find Full Text PDFBiomed Eng Online
November 2024
Institute for Biomedical Engineering, Rostock University Medical Center, Friedrich-Barnewitz-Str. 4, 18119, Rostock, Germany.
Background: Chronic venous insufficiency (CVI) is a common disease with a high prevalence. Incompetent venous valves are considered as one of the main causes. Besides compression therapy, various surgical therapies are practiced, whereby the reconstruction of valves is of central importance.
View Article and Find Full Text PDFPharmaceuticals (Basel)
October 2024
Division of Cardiology and CardioLab, Department of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.
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