Mimosa, an excellent energy crop candidate because of its high growth yield, also contains, on a dry basis, 0.83% hyperoside and 0.90% quercitrin. Hyperoside has been documented as having anti-inflammatory and diurectic properties, whereas quercitrin may play a role in intestinal repair following chronic mucosal injury. Thus, mimosa might first be extracted for important antioxidant compounds and then used as a feedstock for energy production. This article presents results from studies aimed at determining the effect of three extraction parameters (temperature, solvent composition, and time) on the yield of these important quercetin compounds. Conditions are sought which maximize yield and concentration, whereas complementing subsequent biomass pretreatment, hydrolysis and fermentation.
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http://dx.doi.org/10.1385/abab:130:1:382 | DOI Listing |
Molecules
December 2024
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
has great value and development prospects in hypolipidemic applications. In this study, we comprehensively screened out multi-index components relevant to the quality of based on the hypolipidemic function of the flavonoid fraction of (FFN) combined with chemical characterizations. Firstly, in vitro antioxidant and cell experiments evaluated the hypolipidemic function of the FFN.
View Article and Find Full Text PDFBiomed Pharmacother
December 2024
Key Laboratory of Neuropsychiatric Drug Research of Zhejiang Province, Hangzhou medical college, Hangzhou, Zhejiang 310013, PR China. Electronic address:
Ziziphora clinopodioides Lam. (Z. clinopodioides) is a traditional Chinese and ethnic medicine in Xinjiang, China with various therapeutic effects.
View Article and Find Full Text PDFInt Immunopharmacol
January 2025
State Key Laboratory of Pharmaceutical Biotechnology, College of Life Sciences, Nanjing University, Nanjing 210023, China. Electronic address:
Sepsis-induced acute lung injury (ALI) is a life-threatening condition associated with high morbidity and mortality rates in intensive care units (ICUs). Emerging evidence from clinical studies suggests that compounds derived from traditional Chinese medicine (TCM) have shown promising therapeutic effects in treating sepsis-induced ALI. Hyperoside is a bioactive compound extracted from TCM.
View Article and Find Full Text PDFInt Immunopharmacol
January 2025
College of Pharmacy, Key Laboratory of Protection, Development and Utilization of Medicinal Resources in Liupanshan Area, Ministry of Education, Ningxia Medical University, Yinchuan, Ningxia 750004, China; Ningxia Regional Characteristic Traditional Chinese Medicine Collaborative Innovation Center Co-constructed by the Province and Ministry, Ningxia Engineering and Technology Research Center for Modernization of Regional Characteristic Traditional Chinese Medicine, Ningxia Medical University, Yinchuan 750004, China. Electronic address:
The primary objective of this study was to investigate the potential pharmacological effects of Hyperoside (Hyp) extract on chronic social defeat stress (CSDS)-induced depression-like behavior in mice. We established CSDS mice to evaluate the antidepressant effects of Hyp. Additionally, We assessed the changes in neuroinflammatory factors in the TRX1/NLRP1/Caspase-1 signaling pathway using adeno-associated virus (AAV) and BV2 microglial cells.
View Article and Find Full Text PDFFood Funct
November 2024
State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Phyllanthi Fructus (PF) is a tropical fruit with the potential to effectively reduce postprandial blood glucose. However, the lack of quantitative evaluation methods and comprehensive understanding of hypoglycemic active compounds has hindered the development and application of functional foods and dietary supplements derived from PF. In this study, based on the "mass reaction parallel line method", with acarbose as the control and PF extract as the test material, a biological evaluation method for PF hypoglycemic activity based on α-glucosidase inhibition was established for the first time.
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