[Clinical study on Dan Shao Tang in treating diabetic nephropathy of deficiency of Yin with damp-heat symptom].

Objective: To explore the effect of Dan Shao Tang (DST) in treating diabetic nephropathy (DN) of deficiency of Yin with damp-heat symptom.

Methods: The 72 patients with DN of deficieny of Yin with damp-heat symptom were randomly divided into two groups. Among them, the 42 patients in treatment group were treated with DST and western medicine and the 30 patients in control group were treated only with western medicine. Before and after treatment, the effect and indexes change including blood glucose, renal function, proteinuria, microproteins, lipid metabolism and hyperviscosity were observed.

Results: After three months treatment, the general effective rate in treatment group was 76.19%, which was markedly higher than that in control group (50.00%, P < 0.01). Moreover, treatment group was obviously better than control group on decreasing blood glucose proteinuria and microproteins, improving renal function, ameliorating lipuid metabolism and hyperviscosity (P < 0.01 or P < 0.05).

Conclusion: DST is effective ton treatment on DN of deficiency of Yin with damp-heat symptom.