Caries prevention. Today there is enough scientific knowledge about the etiology of caries and factors that might interfere in this process in order to develop preventive strategies. Pathological factors including acidogenic bacteria (e.g. mutans streptococci and lactobacilli), salivary disfunction and dietary carbohydrates are related to caries progression. Protective factors--which include salivary calcium, phosphate and proteins, salivary flow, fluoride, and antibacterial components or agents--can balance, prevent or reverse dental caries. Two strategies have been described in preventive medicine: (1) the population strategy, which in aimed at a general reduction of the risk factors for all the individuals in the population, whether diseased or not; (2) the high-risk strategy, which aims at targeting the program at those individuals with the highest risk. As caries progression or reversal is determined by the balance between protective and pathological factors, caries prevention should be given high priority not only by physicians (general, paediatric, paediatric dentist) but also by schools and even the governmental authorities. More time should be spent giving the right informations to the population regarding dietary habits and programs of nutritional education, oral hygiene routines and fluoride exposure.
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Arch Oral Biol
January 2025
State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China. Electronic address:
Objectives: The present study aimed to explore the inhibitory effect of taxifolin (TAX) on Streptococcus mutans (S. mutans) in vitro and evaluated the anti-caries efficacy of TAX in vivo.
Design: The anti-microbial and anti-biofilm properties of TAX were examined on the S.
Int J Paediatr Dent
January 2025
SAMRC/Developmental Pathways for Health Research Unit, Department of Paediatrics, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Background: Children with special healthcare needs (CSHCN) experience higher unmet dental treatment needs than their healthy peers (NSHCN).
Aim: We compared dental treatment received by CSHCN and NSHCN at academic dental hospitals in South Africa (SA).
Design: Clinical records of 1-16-year-old children who had dental treatment under general anaesthetic (GA) between 2017 and 2023 were reviewed.
PLoS One
January 2025
Dentistry Research Institute, Research Center for Caries Prevention, Tehran University of Medical Sciences, Tehran, Iran.
World Health Organization invites the nations to progress towards universal health care coverage. This study evaluated preventive and curative dental services utilization among children aged 12 years and younger in Tehran, Iran, based on the Andersen behavioral model using a generalized structural equation modeling. A phone-based cross-sectional study was conducted in Tehran, Iran, on 886 children in 2023.
View Article and Find Full Text PDFSci Rep
January 2025
Institute of Biology (Inbio), Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil.
This study assessed the effect of composite resins, aggregated or not with S-PRG particles, and the use of toothpaste in controlling demineralization and bacterial growth. Human molars were distributed into 3 groups: control (CT) - sound teeth, Beautifil Bulk Restorative System (aggregated with S-PRG) (BB), Filtek One Bulk Fill (without S-PRG) (FB). Teeth destined for groups BB and FB previously received Class I preparations (4 × 4 × 4 mm), followed by single-increment restorations.
View Article and Find Full Text PDFInt Dent J
January 2025
Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Bunkyo-ku, Tokyo, Japan.
Introduction And Aims: Marginal sealing by enamel bonding is important to enhance the durability of the restoration and prevent secondary caries after operative procedure. This study aimed to evaluate the enamel acid resistance and bond strength of an experimental calcium-containing adhesive system.
Methods: All materials were provided by Kuraray Noritake Dental, Inc.
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