Septic arthritis of the shoulder, elbow, or wrist is not commonly described in the literature. We evaluated the micro- biology of these infections and the diagnostic role of joint aspirate findings. This retrospective study includes 52 patients, diagnosed from 1994 to 2004, with septic arthritis of the shoulder (n = 17), elbow (n = 23), or wrist (n = 12). The mean age was 44.3 years, and 54% of patients (28/52) had comorbidities. The prevalence of Staphylococcus aureus was 76%. Ninety-six percent of aspirates with positive cultures had a polymorphonuclear differential count greater than 85% of the total aspirate white blood cell count. Staphylococcus aureus is the most prevalent organism. A high index of suspicion for septic arthritis is necessary for all patients with upper extremity joint complaints, irrespective of age and medical status. The joint aspirate differential white blood cell count may be helpful in the diagnosis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/01.blo.0000229322.30169.29 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
MRSA septic arthritis of the pubic symphysis post vaginal delivery: A case report and literature review.
Int J Surg Case Rep
January 2025
Department of Surgery, Orthopaedic Division, Sultan Qaboos University Hospital, Muscat, Oman.
Introduction And Importance: Septic arthritis of the pubic symphysis is a rare postpartum infection characterized by severe pelvic pain, fever, and elevated inflammatory markers. It is often underdiagnosed due to its rarity and nonspecific symptoms. It is commonly caused by Staphylococcus aureus, with methicillin-resistant Staphylococcus aureus (MRSA) septic being a rare but concerning pathogen.
View Article and Find Full Text PDFPrion protein modulation of virus-specific T cell differentiation and function during acute viral infection.
Immunohorizons
January 2025
Center for Virus Research, Chao Family Comprehensive Cancer Center, Department of Molecular Biology and Biochemistry, Charlie Dunlop School of Biological Sciences, University of California, Irvine, Irvine, CA, United States.
The differentiation and functionality of virus-specific T cells during acute viral infections are crucial for establishing long-term protective immunity. While numerous molecular regulators impacting T cell responses have been uncovered, the role of cellular prion proteins (PrPc) remains underexplored. Here, we investigated the impact of PrPc deficiency on the differentiation and function of virus-specific T cells using the lymphocytic choriomeningitis virus (LCMV) Armstrong acute infection model.
View Article and Find Full Text PDFDrug-drug interaction between ensitrelvir and tacrolimus in a patient undergoing treatment for COVID-19: a case report.
J Pharm Health Care Sci
January 2025
Department of Pharmacy, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.
Background: Ensitrelvir is a novel SARS-CoV-2 3-chymotrypsin-like protease inhibitor, similar to nirmatrelvir/ritonavir. Several case reports have demonstrated the efficacy of 3-chymotrypsin-like protease inhibitors in treating prolonged coronavirus disease 2019 (COVID-19) in immunocompromised patients. Tacrolimus (TAC) is a widely used immunosuppressive agent whose blood level can increase significantly due to the inhibition of cytochrome P450 3A (CYP3A) and P-glycoprotein by nirmatrelvir/ritonavir.
View Article and Find Full Text PDFExploring the shared gene signatures and mechanism among three autoimmune diseases by bulk RNA sequencing integrated with single-cell RNA sequencing analysis.
Front Mol Biosci
January 2025
Department of Neurology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Background: Emerging evidence underscores the comorbidity mechanisms among autoimmune diseases (AIDs), with innovative technologies such as single-cell RNA sequencing (scRNA-seq) significantly advancing the explorations in this field. This study aimed to investigate the shared genes among three AIDs-Multiple Sclerosis (MS), Systemic Lupus Erythematosus (SLE), and Rheumatoid Arthritis (RA) using bioinformatics databases, and to identify potential biomarkers for early diagnosis.
Methods: We retrieved transcriptomic data of MS, SLE, and RA patients from public databases.
Arthritis: Septic Arthritis.
FP Essent
January 2025
Family medicine residency program at Rutgers University/Robert Wood Johnson University Hospital Somerset, Somerville, NJ.
Septic arthritis is acute onset of monoarticular inflammation of a joint due to an infectious etiology. It is usually bacterial but can be viral or fungal. Septic arthritis causes significant morbidity and mortality and requires prompt diagnosis and treatment.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!