AI Article Synopsis
- Renal cortical blood flow can be effectively measured using power Doppler ultrasound (PDUS), and the study aimed to see if this blood flow decreases during burn shock but improves with resuscitation in pigs.
- Eight pigs suffered a severe burn, and their kidney blood flow was assessed using both direct methods and PDUS before and after resuscitation efforts.
- The results showed that PDUS readings dropped significantly after the burn but recovered during resuscitation, indicating that PDUS is a better indicator of renal blood flow than urine output in these situations.
Article Abstract
Background: Renal cortical blood flow can be quantified by means of power Doppler ultrasound (PDUS) image analysis. We hypothesized that renal cortical perfusion, estimated by PDUS image intensity (PDUSII), would decrease during burn shock and improve during resuscitation in a porcine model.
Methods: Eight anesthetized swine sustained a 75% scald injury. Resuscitation began 6h postburn. Renal cortical blood flow was measured directly using fluorescent microspheres (CORFLO), and was estimated noninvasively by PDUSII. PDUSII, CORFLO, and cardiopulmonary data were recorded every 2h.
Results: PDUSII decreased significantly from preburn to postburn hour 6, and increased with resuscitation by hour 8. CORFLO correlated well with PDUS image intensity (n=48, r(2)=0.696) but poorly with urine output (n=48, r(2)=0.252).
Conclusion: PDUS in this study was superior to the urine output in assessing renal cortical microvascular blood flow during shock and resuscitation, and may be useful in the care of injured patients.
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| http://dx.doi.org/10.1016/j.burns.2006.01.017 | DOI Listing |
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