Cone-beam computed tomography (CBCT) systems for craniofacial imaging are now available from several manufacturers. CBCT potentially provides opportunities for 3-dimensional cephalometrics in orthodontic assessment of bony landmarks and air-bounded surfaces such as the facial skin. Two-dimensional cephalogram simulation could facilitate the transfer of growth projections from existing data sets as a starting point for use of a new 3-dimensional paradigm. Three methods are described to simulate conventional 2-dimensional cephalograms from CBCT images and volumetric data sets. However, certain precautions are required to assure that selection criteria and imaging parameters guarantee a radiation dose that is as low as reasonably achievable.
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http://dx.doi.org/10.1016/j.ajodo.2005.10.021 | DOI Listing |
Objectives: Bennett's fracture, the most common intra-articular fracture occurring at the base of the thumb, accounts for less than 1% of all hand fractures. It typically results from specific traumatic mechanisms, deforming forces, and ligamentous injuries. To compare the functional outcomes and sequelae in patients with Bennett's fracture treated surgically using: Open reduction and internal screw fixation, closed reduction and percutaneous fixation, arthroscopy-assisted reduction and screw fixation.
View Article and Find Full Text PDFBMJ Oncol
January 2024
Department of Oncology, University of Oxford, Oxford, UK.
Repurposing established non-cancer drugs for the treatment of cancer offers potential benefits such as speed of clinical translation and financial efficiencies. In this study, we assess the landscape of repurposing drugs for combined use with radiotherapy (RT) based on their capacity to increase tumour radiosensitivity. Using a literature-based approach, we identified 42 radiosensitising drugs with varied non-cancer indications and mechanisms of action, that have entered or completed clinical trials in combination with RT or with chemoradiotherapy.
View Article and Find Full Text PDFPan Afr Med J
January 2025
Cardiovascular Department, The Affiliated People´s Hospital of Ningbo University, Ningbo, 315000, ZheJia, China.
This case presents a patient who experienced hypoxia and hypotension following the infusion of industrial-grade anhydrous ethanol into the vein of Marshall (VOM) during atrial fibrillation radiofrequency ablation. The hypotension lasted for at least three days, requiring dopamine support, while hypoxia persisted for over a week. The prolonged nature of these symptoms posed a diagnostic challenge.
View Article and Find Full Text PDFOTA Int
March 2025
Orthopaedic Trauma Institute, Institute for Global Orthopaedics and Traumatology, Department of Orthopaedic Surgery, University of California San Francisco, San Francisco, CA.
Purpose: With life expectancies increasing worldwide, there is a concomitant rise in the incidence of fragility fractures. As such, low-income and lower-middle-income countries (LICs and LMICs) will be faced with increased incidences of hip fractures. The care of these fractures is adversely affected by various factors that include under-resourced healthcare systems and large socioeconomic disparities, which disproportionately affect patient care in these regions relative to high-income countries.
View Article and Find Full Text PDFJ Law Med Ethics
January 2025
MEDICAL COLLEGE OF WISCONSIN, MILWAUKEE, MILWAUKEE, WI, USA.
The introduction of portable MRI (pMRI) has the potential to directly impact dementia research and ultimately clinical care. In this paper, we explore two ethical challenges facing the introduction of pMRI in dementia research. The first is the need to ensure that pMRI enhances rather than undermines efforts aimed at improving ethnoracial representation in dementia research.
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