Idiopathic reversible renal failure in a young woman with minimal change glomerulonephritis.

Saudi J Kidney Dis Transpl

Department of Nephrology, Dammam Central Hospital, Kanoo Kidney Center, Saudi Arabia.

Published: June 2006

AI Article Synopsis

  • A 19-year-old Saudi female presented with nephrotic syndrome, with a renal biopsy indicating minimal change glomerulonephritis (MCGN).
  • After developing oliguric renal failure, she required five weeks of hemodialysis but eventually her renal function fully recovered.
  • Throughout a two-year follow-up, she experienced two relapses of nephrotic syndrome, both successfully treated with corticosteroids, and her acute renal failure was found to be without any clear cause.

Article Abstract

We report a 19-year-old Saudi female with nephrotic syndrome whose renal biopsy revealed findings suggestive of minimal change glomerulonephritis (MCGN). She developed oliguric renal failure requiring hemodialysis. She remained dialysis dependent for five weeks and subsequently renal function recovered fully. She remained nephrotic and responded to a six week course of corticosteroids. She was followed for two years during which she had two relapses, which responded to steroids. Acute renal failure is uncommon in MCGN and is due to acute tubular necrosis induced by hypovolemia or drugs. This patient did not have any obvious precipitating factor, which led to acute reversible renal failure.

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