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Vialinin B, a novel potent inhibitor of TNF-alpha production, isolated from an edible mushroom, Thelephora vialis. | LitMetric
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Vialinin B, a novel potent inhibitor of TNF-alpha production, isolated from an edible mushroom, Thelephora vialis.

Chun Xie Hiroyuki Koshino Yasuaki Esumi Jun-ichi Onose Kunie Yoshikawa Naoki Abe

Bioorg Med Chem Lett

Department of Nutritional Science, Faculty of Applied Bio-Science, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo 156-8502, Japan.

Published: October 2006

A novel dibenzofuran compound designated vialinin B was isolated from dry fruiting bodies of an edible mushroom, Thelephora vialis, and potently inhibits TNF-alpha production in RBL-2H3 cells (IC(50)=0.02nM) and is a promising anti-allergic agent.

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 Source
http://dx.doi.org/10.1016/j.bmcl.2006.07.068DOI Listing

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