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Treatment Analysis of Very Early and Early Onset Psychosis in the Youth Inpatient Setting.
HCA Healthc J Med
December 2024
St George's University, Grenada, West Indies.
Background: The United States Food and Drug Administration approved 6 atypical antipsychotics for pediatric treatment of schizophrenia. However, little has been published on the effectiveness of these medications in the acute treatment setting of adolescents with psychosis. Since the clinical uncertainty and poor prognosis proceeding the early onset of schizophrenia has a significant impact on a child's development, there is a critical need for evidence-based data on this population.
View Article and Find Full Text PDFPsychosis in Laurence-Moon Syndrome: A Case Report.
Cureus
October 2024
Department of Psychiatry, King Saud University, Riyadh, SAU.
Background: Laurence-Moon syndrome (LMS) is a rare autosomal recessive genetic disorder characterized by a combination of neurological, visual, and endocrine abnormalities. The coexistence of psychiatric disorders in LMS patients can complicate clinical management due to the intricate interplay between neurodevelopmental and psychiatric symptoms. A review of the literature failed to identify a similar case study published in major databases, including PubMed, highlighting the significance of this case report.
View Article and Find Full Text PDFBackground: CDKL5 deficiency disorder (CDD) is an early-onset developmental and epileptic encephalopathy. While a subset of individuals is believed to experience comorbid behavioral disorders, none have reported well-defined affective disorders. Though there is a documented association between epilepsy and mood disorders, they may go undetected in the CDD population due to difficulty assessing mood in the presence of severe/profound intellectual disability and disease-related sleep dysregulation.
View Article and Find Full Text PDFAn update on the pharmacological management of Tourette syndrome and emerging treatment paradigms.
Expert Rev Neurother
October 2024
Department of Neurology, Parkinson's Disease Center and Movement Disorders Clinic, Baylor College of Medicine, Houston, TX, USA.
Article Synopsis
- Tourette syndrome (TS) is a childhood-onset disorder with tics, and medication is recommended when symptoms significantly impact life quality.
- The article reviews the types of tics, diagnostic criteria, and various pharmacotherapy options, including those currently being researched.
- Individualized treatment plans are crucial; behavioral therapy is the first choice, while medications like alpha-2 agonists, antipsychotics, and botulinum toxin injections may be considered based on severity and side effects.
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