[Proteolytic activity of Candida albicans strains isolated from women's genital organs with clinical diagnosis of mycosis].

Wiad Parazytol

Ośrodek Leczenia Chorób Pasozytniczych i Grzybic Katedry Biologii i Parazytologii Lekarskiej, Akademia Medyczna, 90-436 Lódź, al. Kościuszki 85.

Published: October 2006

The aim of the presented study was to assess the in vitro activity of aspartate proteinase of strains isolated from women's genital organs with clinical diagnosis of mycosis. We have evaluated the activity of proteinase of 75 Candida albicans strains using Staib method with Rózga modification, in agar medium with human albumin at pH 4.6. The proteolysis zone ranged from 4.0 to 11.0 mm. The values of proteolysis zones in human albumin of C. albicans were similar to left-oblique normal distribution. High and extremely high proteolytic activity is characteristic for more than 50% of strains.

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