This report concerns a patient with symptomatic lung metastases from an epithelial-myoepithelial carcinoma of the submandibular gland. Although the efficacy of chemotherapy is unknown in this disease, our patient was treated with cisplatin combined with 5-fluorouracil and later with paclitaxel and cyclophosphamide. Chemotherapy allowed disease stabilization and relief of the pulmonary symptoms. This is the first report on the use of chemotherapy in this very rare salivary gland carcinoma.
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http://dx.doi.org/10.1007/s00405-006-0125-8 | DOI Listing |
J Ayub Med Coll Abbottabad
December 2024
Armed forces institute of Pathology, Rawalpindi-Pakistan.
Adenomyoepithelioma (AME) is a rare variant of breast neoplasm. It is a biphasic tumour characterized by small epithelial-lined spaces with inner luminal cells and outer of abluminal (myoepithelial) cells. Either - or both - of these two cells may rarely undergo malignant transformation.
View Article and Find Full Text PDFCancer Control
November 2024
Shanda North Road Branch, Jinan Stomatological Hospital, Jinan, People's Republic of China.
Objective: The clinical characteristics and prognosis of primary epithelial-myoepithelial carcinoma of salivary gland (EMC-SG) have not been defined well due to its rarity. The purpose of this study is to assess the proportion of EMC-SG among salivary gland cancers, describe the clinicopathological features and prognosis of this disease, further analyze the factors associated with EMC-SG survival, and establish individual survival-predicting models.
Methods: Data on patients diagnosed with salivary gland malignancy between 2000 and 2020 were collected from the Surveillance, Epidemiology, and End Results database.
Head Neck Pathol
November 2024
Guangdong Provincial Key Laboratory of Translational Medicine in Lung Cancer, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, 106 Zhongshan 2nd Road, Guangzhou, 510080, China.
Oncol Lett
January 2025
Department of Ultrasound Medicine, Affiliated Hospital of Jining Medical University, Jining, Shandong 272029, P.R. China.
Epithelial-myoepithelial carcinoma (EMC) is a rare low-grade malignant tumor with uncommon regional lymph node metastasis and distant metastasis. The diagnosis of this disease primarily relies on the examination of pathological morphology and immunohistochemical staining, as its clinical symptoms and imaging findings are non-specific. This makes it more difficult to provide specific information about EMC lung metastasis.
View Article and Find Full Text PDFJ Stomatol Oral Maxillofac Surg
October 2024
Department of Pathology, School of Medical Sciences, Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazil. Electronic address:
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