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Endogenous reward (intrinsic reward at will) is a that is by steps toward any goals which are challenging and/or uncommon enough to prevent its debasement by inflation. A "theory of mental computational processes" should propose what properties let goals grow from appetites for endogenous rewards. Endogenous reward may be the universal selective factor in all modifiable mental processes.

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Purpose: To assess the efficacy of clinical exome sequencing (CES) in individuals involved in assisted reproductive technology (ART) or sperm donor programs, with a specific focus on its impact on clinical decision-making.

Methods: A total of 3991 individuals without a family history of genetic disorders underwent CES targeting 5595 genes at a reproductive center between December 2022 and April 2024. The cohort comprised 217 sperm donors, 232 female recipients, and 1771 couples (3542 patients) undergoing ART with their own gametes.

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Dissociable effects of perceived control on reward-related neural dynamics under risk and ambiguity.

Neuroimage

January 2025

Department of Psychology, Guangzhou University, Guangzhou, China; Center for Reward and Social Cognition, School of Education, Guangzhou University, Guangzhou, China. Electronic address:

Perceived control plays a crucial role in risk-taking behavior, but its neural effect on reward dynamics in risky and ambiguous decision making remains unclear. Here, we addressed this issue by measuring participants' (N = 40) EEG activity while they were performing a wheel-of-fortune task. Participants either made choices themselves (a high control condition) or followed the computer's choice (a low control condition) under risky or ambiguous decision contexts.

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Promoting autonomy in medical decision-making is an essential part of palliative care. Therefore, palliative care providers should prioritize supporting the autonomy of sexual and gender minority (SGM) older adults, a community that has historically suffered from healthcare disparities. This support is particularly significant when an illness or injury renders a patient unable to make medical decisions, necessitating the designation of a surrogate decision-maker.

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The impact of visual fidelity on screen-based virtual reality food choices: A randomized pilot study.

PLoS One

January 2025

Department of Nutrition, College of Human Health and Development, The Pennsylvania State University, University Park, PA, United States of America.

Objective: To understand the impact of fidelity and perceived realism on virtual reality food choices, and task motivation, engagement, and interest.

Design: Randomized controlled trial.

Setting: Online.

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