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Food Safety Evaluation of Recombinant Humanized Type III Collagen Produced by Komagataella phaffii SMD1168-2COL3.
J Appl Toxicol
January 2025
College of Food Science and Nutritional Engineering, China Agricultural University, Beijing, China.
Collagens are biofunctional proteins that have been widely used in many fields, including biomedical, cosmetics, and skin care for their value in maintaining the integrity of cellular membranes. Collagens are also commonly consumed in foods and provide a source of protein and amino acids. As part of the safety assessment for this particular recombinant humanized type III (RHTypeIII) collagen produced by Komagataella phaffii SMD1168-2COL3, a series of toxicological tests were conducted.
View Article and Find Full Text PDF[Research progress on pollen monitoring and pollen allergenicity of ragweed].
Zhonghua Yu Fang Yi Xue Za Zhi
December 2024
Department of Allergy, ShengJing Hospital of China Medical Universty, Shenyang110000, China.
Ragweed, as an exotic invasive species, which is one of the most important allergens for hay fever, has been invading China for more than 80 years. The increasing number of people with hay fever makes effective treatment, as well as the prevention and control of pollen transmission critical. This article delves into a comprehensive research summary focusing on the allergenic properties of ragweed pollen, its pathogenic characteristics, epidemiological patterns, monitoring and control measures, as well as concentrated management approaches.
View Article and Find Full Text PDF(ragweed) pollen - A growing aeroallergen of concern in South Africa.
World Allergy Organ J
December 2024
Division of Allergology and Clinical Immunology, Department of Medicine, University of Cape Town, Cape Town, South Africa.
Background: Ragweed is an invasive, highly allergenic weed predicted to expand its habitat with warming global temperatures. Several species have been identified in South Africa for well over a century; however, its presence remained undetected by allergists and aerobiologists until the development of an extensive aerospora monitoring system across South African urban areas since 2019. This paper presents the inventory of preliminary investigation of the airborne pollen and the taxonomic identification of ragweed species.
View Article and Find Full Text PDFReal-World Study of Ragweed Sublingual Immunotherapy in Hungary.
Allergol Immunopathol (Madr)
September 2024
University of Pécs, Szigetvár, Hungary.
Background: Ragweed () has become invasive in Europe, causing significant respiratory issues. Subcutaneous allergen immunotherapy (SCIT) has long been used to manage pollen allergies, but sublingual immunotherapy (SLIT) has gained interest.
Objective: This study aimed to evaluate the clinical benefits of ragweed SLIT under real-world in a cohort of Hungarian patients allergic to ragweed pollen.
Fungi-sensitized individuals have unique profiles where Alt a 1 dominates promoting response to grass, ragweed and cat allergens.
Front Allergy
August 2024
Department of Allergology, SI Institute of Otolaryngology n.a. Prof.O.S. Kolomiychenko of NAMS of Ukraine, Kyiv, Ukraine.
Introduction: The aim of our work was to determine comprehensively the sensitization profile of patients hypersensitive to fungal allergenic components in the Ukrainian population, identifying features of their co-sensitization to allergens of other groups and establishing potential relationships between causative allergens and their ability to provoke this hypersensitivity.
Methods: A set of programs was developed using Python and R programming languages, implementing the K-means++ clustering method. Bayesian networks were constructed based on the created clusters, allowing for the assessment of the probabilistic interplay of allergen molecules in the sensitization process of patients.
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