AI Article Synopsis
- The study aimed to identify low plasma glucose levels that indicate profound hypoglycemia in newborns.
- Over 95% of the 89 infants analyzed had plasma glucose levels below 25 mg/dL, detected after 10 hours of age.
- Among infants experiencing similar low glucose levels, 21% had neurological injuries related to hypoglycemia, with a 95% confidence interval of 14% to 27%.
Article Abstract
The study goal was to define low thresholds of plasma glucose concentrations that constitute profound hypoglycemia. Population analysis was performed on research publications on neonatal hypoglycemia ascertained by a Medline search. Eligible patients had neurological sequelae associated directly and primarily with hypoglycemia (profound hypoglycemia). Of 89 infants, more than 95% had plasma glucose levels of less than 25 mg/dL that were first detected at more than 10 hours of age. A breakdown of study patients according to those with or without neurological sequelae, who were exposed to a similar degree of hypoglycemia, showed a combined incidence of neurological injury of 21%, with 95% confidence interval from 14% to 27%.
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| http://dx.doi.org/10.1177/0009922806290610 | DOI Listing |
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