AI Article Synopsis
- The report aims to help primary care physicians easily identify children with impaired kidney function, which is crucial due to the high rates of chronic kidney disease in adults.
- Comparative studies were conducted on 32 pediatric patients over 8 years, checking glomerular filtration rate (GFR) through both cimetidine clearance and formulas based on height and serum creatinine.
- If a child aged 1 year or older has a calculated GFR of less than 60 mL/min/1.73 m², it indicates significantly reduced GFR, warranting a referral to a pediatric nephrologist for further assessment.
Article Abstract
This report is to provide primary care physicians with a convenient method for identifying children with impaired kidney function. This is important because of the prevalence of chronic kidney disease in adults and because intervention may delay disease progression. The glomerular filtration rate (GFR) measured using cimetidine clearance and calculated using height and serum creatinine concentration were compared during 222 clearance studies in 32 pediatric patients over 8 years. A child 1 year or older with a calculated GFR<60 mL/min/1.73 m2 has a significantly reduced GFR and should be referred to a pediatric nephrologist for further evaluation.
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| http://dx.doi.org/10.1177/0009922806290568 | DOI Listing |
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