The correlation between scores on the Barratt Impulsiveness Scale (BIS) and activation measured by functional magnetic resonance imaging in a dorsolateral prefrontal cortical (DLPFC) activating task was examined in 15 MDMA-using subjects and 19 controls. A significant correlation between BIS scores and DLPFC activation was found, supporting a role for the DLPFC in BIS-measured impulsivity.
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http://dx.doi.org/10.1016/j.pscychresns.2006.01.014 | DOI Listing |
Hum Brain Mapp
December 2024
Department of Neuroscience, High Resolution Brain Imaging Lab, Baylor College of Medicine, Houston, Texas, USA.
In functional magnetic resonance imaging, the hemodynamic response function (HRF) is a stereotypical response to local changes in cerebral hemodynamics and oxygen metabolism due to briefly (< 4 s) evoked neural activity. Accordingly, the HRF is often used as an impulse response with the assumption of linearity in data analysis. In cognitive aging studies, it has been very common to interpret differences in brain activation as age-related changes in neural activity.
View Article and Find Full Text PDFJ Affect Disord
December 2024
Amsterdam UMC, Vrije Universiteit Amsterdam, Dept. Anatomy and Neurosciences, De Boelelaan 1117, Amsterdam, Netherlands; Amsterdam UMC, Vrije Universiteit Amsterdam, Dept. Psychiatry, De Boelelaan 1117, Amsterdam, Netherlands; Amsterdam Neuroscience, Compulsivity Impulsivity Attention Program, Amsterdam, Netherlands. Electronic address:
Obsessive-compulsive disorder (OCD) is linked with dysfunction in frontal-striatal, fronto-limbic, and visual brain regions. Research using proton magnetic resonance spectroscopy (H-MRS) suggests that altered neurometabolite levels, like glutamate, may contribute to this dysfunction. However, static neurometabolite levels in OCD patients have shown inconsistent results, likely due to previous studies' limited focus on neurometabolite dynamics.
View Article and Find Full Text PDFDev Cogn Neurosci
June 2024
Department of Psychology, University of Wisconsin at Milwaukee, Milwaukee, WI 53201, United States. Electronic address:
Adolescence is characterized by dynamic neurodevelopment, which poses opportunities for risk and resilience. Adverse childhood experiences (ACEs) confer additional risk to the developing brain, where ACEs have been associated with alterations in functional magnetic resonance imaging (fMRI) BOLD signaling in brain regions underlying inhibitory control. Socioenvironmental factors like the family environment may amplify or buffer against the neurodevelopmental risks associated with ACEs.
View Article and Find Full Text PDFBackground Patients with psychotic disorders have a higher risk of physical illnesses on account of genetic predisposition, poorer access to healthcare, medication use, environmental factors and lifestyle. Because healthy lifestyle behaviour is established at young age, it is important to signal problems in good time. A lifestyle screening might be useful in this respect.
View Article and Find Full Text PDFJ Phys Ther Educ
December 2023
Sheri R. Kiami is an associate clinical professor in the Department of Physical Therapy, Movement & Rehabilitation Sciences at Northeastern University, 301 Robinson Hall, 360 Huntington Avenue, Boston, MA 02115 ( ). Please address all correspondence to Sheri R. Kiami.
Background And Purpose: To address racial and ethnic disparities, physical therapy organizations, educational institutions, and clinical practices seek to advance diversity, equity, inclusion (DEI), and social justice in health care. Although our professional organizations have crafted proclamations, resource lists, developed new accreditation standards, and strategic plans, we lack a unifying framework and action tools for substantial and sustained progress. In addition, the DEI acronym is missing the essential element of belonging (B), that is, sharing a sense of purpose and feeling safe to contribute opinions as a valued member of an organization.
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