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Five cases of transient anterior subcapsular vacuolar lens opacities following trabeculectomy using a dispersive ophthalmic viscosurgical device (OVD) performed by the same surgeon were reviewed at Shimane University Hospital from February to June 2024. All cases presented with anterior vacuolar subcapsular lens opacities observed seven days after surgery, which gradually resolved without specific interventions. Detailed surgical records and clinical outcomes were collected, and the findings suggest that these opacities, characterized by their transient and vacuolar appearance, should be recognized as an early complication of trabeculectomy, potentially linked to the use of dispersive OVDs.
View Article and Find Full Text PDFHistopathology of incidental non-neoplastic findings in transgenic CByB6F1-Tg(HRAS)2Jic mice used in toxicity studies.
J Toxicol Pathol
January 2025
Labcorp Early Development Laboratories, Inc., 3635 Concorde Parkway, Suite 100, Chantilly, VA, 20151, USA.
This technical report presents a collection of illustrative images and concise descriptions of non-neoplastic microscopic findings noted in transgenic CByB6F1-Tg(HRAS)2Jic (Tg.rasH2) mice from 26-week-carcinogenicity studies. A unique finding in the Tg.
View Article and Find Full Text PDFAcute Pyelonephritis Complicated With Spontaneous Subcapsular Renal Hematoma: A Case Report.
Cureus
November 2024
Internal Medicine, Centro Hospitalar de Trás-Os-Montes e Alto Douro, Vila Real, PRT.
Spontaneous subcapsular renal hematoma is a rare condition defined as spontaneous hemorrhage confined to the subcapsular and/or perirenal space. Its etiology can vary, ranging from renal tumors to vascular diseases, renal cysts, or infections. Here, we report the case of a 54-year-old male who presented to the emergency department with a two-day history of abdominal pain and fever.
View Article and Find Full Text PDFtransplantation of intrahepatic cholangiocyte organoids with decellularized liver-derived hydrogels supports hepatic cellular proliferation and differentiation in chronic liver injury.
J Mater Chem B
January 2025
Department of Molecular and Cellular Medicine, Institute of Liver and Biliary Sciences, New Delhi, India.
The limited replicative potential of primary hepatocytes (Hep) is a major hurdle for obtaining sufficient quantity and quality hepatocytes during cell therapy in patients with liver failure. Intrahepatic cholangiocyte organoids (ICOs) derived from intrahepatic bile ducts differentiate into both hepatocytes and cholangiocytes . Here, we studied effects of transplanting ICOs and Hep in chronic liver injury mice models.
View Article and Find Full Text PDFClinical Classification and Management Outcomes of Anterior Segment-Dominated Persistent Fetal Vasculature: The CCPMOH Report.
Am J Ophthalmol
December 2024
From the State Key Laboratory of Ophthalmology (H.C., C.L., Z.L., X.L., Y.L., H.L., and W.C.), Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China. Electronic address:
Purpose: To describe clinical features, management, and outcomes of anterior segment-dominated persistent fetal vasculature (aPFV).
Design: A secondary analysis of aPFV data from a longitudinal cohort study.
Methods: The age and gender of each participant upon initial presentation, along with biological parameters, best-corrected visual acuity, and biomicroscopic assessments were collected.
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