Objective: Serum ferritin levels are assumed to be an atherosclerotic risk factor. Ferritin production is increased in individuals with activated liver production, which has been shown in hyperthyroid conditions. An association between subclinical hyperthyroidism and serum ferritin levels would add an explanation to the relation between low serum thyrotropin levels and mortality. The aim of the present analysis was to investigate an association between thyroid function and serum ferritin levels. We hypothesized low serum thyrotropin to be related to high serum ferritin levels.
Design: The Study of Health in Pomerania (SHIP) is a population-based study comprising male and female adults aged 20 to 79 years. Data of 4111 subjects (2071 females) were available for the present analysis. Serum ferritin levels were determined by an immunoturbidimetric assay. Multivariable analyses were performed to investigate an independent relation between thyroid function and serum ferritin levels.
Main Outcome: Age-adjusted and gender-stratified analyses revealed no association between thyroid function and serum ferritin levels, neither in females nor in males. This finding remained stable after adjustment for potential confounders and in sensitivity analyses.
Conclusion: There was no association between thyroid function and serum ferritin levels. We conclude that serum ferritin levels do not account for the relation between subclinical hyperthyroidism and vascular mortality.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1089/thy.2006.16.681 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Bone and Joint Involvement in Beta Thalassemic Patients: A Cross-sectional Study.
Indian J Orthop
January 2025
Dayanand Medical College and Hospital, Tagore Nagar, civil lines, Ludhiana, Punjab 141001 India.
Purpose: There is paucity of guidelines with inadequate data available about the extent and prevention of bone and joint disease in beta-thalassemic patients in Indian population. This study aims to determine bone and joint involvement in beta-thalassemic patients. It evaluates serum biochemical parameters of bone formation and resorption and correlates with the symptomatology in these patients.
View Article and Find Full Text PDFThe role of C-reactive protein and ferritin in the diagnosis of HLH, adult-onset still's disease, and COVID-19 cytokine storm.
Sci Rep
December 2024
International Collaboration On Repair Discoveries, School of Biomedical Engineering, University of British Columbia, Vancouver, BC, Canada.
Cytokine storm syndromes such as hemophagocytic lymphohistiocytosis (HLH), Adult-onset Still's disease (AOSD), and COVID-19 cytokine storm (CCS) are characterized by markedly elevated inflammatory cytokines. However clinical measurement of serum cytokines is not widely available. This study examined the clinical utility of C-reactive protein (CRP) and ferritin, two inexpensive and widely available inflammatory markers, for distinguishing HLH from AOSD and CCS.
View Article and Find Full Text PDFRisk factors for metabolic syndrome in the premetabolic state assessed using hierarchical clustering study in a health screening group.
Sci Rep
December 2024
Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Early detection of a premetabolic status that is at risk for metabolic syndrome (MetS) but not meeting the criteria is crucial. This study examined 27,623 participants aged 20-50 (mean: 40.7) years who underwent initial health screening at Kangbuk Samsung Hospital (2011-2019), focusing on individuals with one or two MetS components.
View Article and Find Full Text PDFDiagnostic abnormalities, disease severity and immunotherapy responsiveness in individuals with Down syndrome regression disorder.
Sci Rep
December 2024
Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Introduction: Down Syndrome Regression Disorder (DSRD) is a neuropsychiatric condition causing insomnia, catatonia, encephalopathy, and obsessive-compulsive behavior in otherwise healthy individuals with Down syndrome (DS). Smaller cohorts have identified heterogenous diagnostic abnormalities which have predicted immunotherapy responsiveness although pattern analysis in a large cohort has never been performed.
Methods: A multi-center, retrospective study of individuals with DSRD was performed.
Micronutrient Biomarkers and Their Association with Malaria Infection in Children in Buea Health District, Cameroon.
Trop Med Infect Dis
December 2024
Biotechnology Unit, University of Buea, Buea, Cameroon.
Recently malaria and micronutrient deficiencies have become a major worldwide public health problem, particularly in Africa and other endemic countries with children under 5 years old being the most vulnerable. Apart from nutritional problems that cause micronutrient deficiencies, studies have also reported that parasitic infections like malaria can affect the levels of micronutrients. Thus, this research was aimed at assessing the serum levels of micronutrient biomarkers and their association with malaria infection in children under 5 years old in the Buea Health District.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!