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Objective: The objective of this retrospective clinical review was to assess the safety and accuracy of intraparotid sentinel node biopsy in patients with melanoma.
Setting: This study was conducted at a tertiary referral center.
Patients: Twenty-eight patients with cutaneous melanoma of the head and neck undergoing sentinel lymph node (SLN) biopsy in which the radionuclide localized to the parotid gland on preoperative lymphoscintigraphy were studied.
Methods: All patients underwent wide local excision of the tumor and intraparotid sentinel node biopsy using intraoperative gamma probe localization.
Results: There were 25 men and 3 women ranging in age from 34 to 81 years. The primary site was on the auricle in 14 patients: temple, 4; forehead, 5; cheek, 3; and on the neck in 2 patients, respectively. The mean Breslow thickness was 2.3 mm (range, 0.9-7.0 mm). In 27 of 28 patients, an intraparotid SLN was identified. In one patient, final pathology did not reveal lymphoid tissue despite a high count in the parotid tissue excised. Median number of SLN per patient was two. Six patients had microscopic metastases in the SLN. In two of these patients, additional microscopic lymph node metastases were found in the neck after subsequent formal lymphadenectomy. The pathologic staging for the group (n = 14) was: stage 1B, 4; 2A, 4; stage 2B, 3; and stage 3B, 3 patients, respectively. All patients are alive and without evidence of disease (mean follow up, 31 months). There were no surgical complications, specifically no patient experienced temporary or permanent facial paralysis.
Conclusion: Intraparotid SLN biopsy for staging cutaneous head and neck melanoma is a reliable, accurate, and safe procedure.
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http://dx.doi.org/10.1097/01.mlg.0000225967.93261.fc | DOI Listing |
Ann Surg Oncol
November 2024
Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Background: Surgical management of head and neck cutaneous melanoma (HNCM) has evolved tremendously since sentinel lymph node biopsy (SLNB) has become the prominent tool of prognosis and staging. This meta-analysis aimed to evaluate the safety and efficiency of intraparotid SLNB compared with a more extensive surgery of superficial parotidectomy (SP).
Methods: The electronic database of PubMed and Scopus were searched for publications until 10 March 2022.
Laryngoscope
July 2020
Department of Dermatology, Michigan Medicine, University of Michigan, Ann Arbor, Michigan, U.S.A.
Objective: Characterize long-term cranial nerve (CN) outcomes following sentinel lymph node biopsy (SLNB) based management for head and neck cutaneous melanoma (HNCM).
Methods: Longitudinal review of HNCM patients undergoing SLNB from 1997-2007.
Results: Three hundred fifty-six patients were identified, with mean age 53.
Int J Clin Oncol
October 2017
Department of Skin Oncology/Dermatology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka, Saitama, 350-1298, Japan.
Background: Most patients with head and neck skin tumors present with normal facial nerve function. A common treatment strategy for these patients is facial nerve preservation surgery, although the degree to which the nerve is successfully preserved is still unclear. Data on the incidence and recovery of facial nerve dysfunction are woefully lacking in the field of dermato-oncology.
View Article and Find Full Text PDFActa Ophthalmol
June 2017
Orbital Oncology and Ophthalmic Plastic Surgery, Department of Plastic Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Background: We sought to update our prior report of findings on sentinel lymph node biopsy (SLNB) and predictors of a positive SLN in patients with conjunctival or eyelid melanoma.
Methods: We reviewed the records of all patients with ocular adnexal melanoma who underwent SLNB at one institution during 2000-2015. We determined rates of positive and false-negative findings on SLNB, primary tumour features correlated with positive findings and rate of nodal recurrence (false-negative event) after negative findings.
Head Neck
September 2014
Department of Oral and Maxillofacial Surgery, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Background: Applications for sentinel node biopsy (SNB) in the head and neck are increasing with new lymphatic tracers and imaging techniques allowing previously inaccessible tumor sites to benefit from the procedure. We show that lymphatic drainage from a primary parotid malignancy can be accurately mapped using navigational surgery.
Methods: A patient with radiologically classified N0 intraparotid malignancy underwent peritumoral injection of 99mTc-nanocolloid.
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