We examined adrenal glands obtained at early autopsy of 56 men aged 21-70 years. According to the age five groups of cases were distinguished. The study was performed with the use of methods of silver impregnation of nerve plexuses and planimetric pointcounting. Density of nerve plexuses in adrenal medulla was significantly increased by 30 years of age due to the development of nervous relations in this organ. After age of 30 years density of nerve plexuses in adrenal medulla remained relatively stable providing high morphofunctional activity of adrenal glands. Morphological and morphometrical changes in nervous plexuses of adrenal medulla of patients were associated with cardiovascular diseases.

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