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Proceedings of the 2024 Division of Translational Toxicology Satellite Symposium.
Toxicol Pathol
December 2024
Wake Forest University, Winston-Salem, North Carolina, USA.
The 2024 annual Division of Translational Toxicology (DTT) Satellite Symposium, entitled "Pathology Potpourri," was held in Baltimore, Maryland, at the Society of Toxicologic Pathology's 42nd annual meeting. The goal of this symposium was to present and discuss challenging diagnostic pathology and/or nomenclature issues. This article presents summaries of the speakers' talks along with select images that were used by the audience for voting and discussion.
View Article and Find Full Text PDFBackground: The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides a comprehensive assessment of health and risk factor trends at global, regional, national, and subnational levels. This study aims to examine the burden of diseases, injuries, and risk factors in the USA and highlight the disparities in health outcomes across different states.
Methods: GBD 2021 analysed trends in mortality, morbidity, and disability for 371 diseases and injuries and 88 risk factors in the USA between 1990 and 2021.
Abstracts from the 42nd Annual Meeting of the Obesity Society at Obesityweek® November 3-6, 2024.
Obesity (Silver Spring)
November 2024
Select Toxicologic Pathology Case Studies of the Hepatobiliary System.
Toxicol Pathol
October 2023
Shionogi & Co., Ltd., Osaka, Japan.
This case study session of the hepatobiliary system was held during the 42nd Annual Society of Toxicologic Pathology Symposium in Summerlin, Nevada. The case studies highlighed potential hepatic and biliary toxicity liabilities. This article comprises several of the case studies that were presented during the session which included copper-associated hepatitis in a dog, sinusoidal obstruction syndrome in non-human primates, hepatic cytoplasmic alteration in mice and rats, and Kupffer cell hyperplasia/granulomatous inflammation in rats.
View Article and Find Full Text PDFCharacteristics and Outcomes of Obstetric Sepsis by Three Sets of Clinical Diagnostic Criteria: A Retrospective Study.
Am J Perinatol
May 2024
Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan.
Article Synopsis
- Pregnancy-related mortality in the U.S. is notably high, and sepsis contributes significantly to these deaths. The study compares three sepsis criteria (Sepsis-2, Sepsis-3, and CMQCC) to evaluate their effectiveness and patient outcomes.
- Analysis of data from the University of Michigan Medical Center shows that while Sepsis-2 identified the majority of patients, there was weak agreement among all three criteria, indicating inconsistencies in diagnosing sepsis.
- The findings suggest that those diagnosed using CMQCC criteria had worse health profiles and higher mortality rates, highlighting the need for improved diagnostic criteria in managing sepsis during pregnancy.
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