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[Effects of afobazole on the BDNF content in brain structures of inbred mice with different phenotypes of emotional stress reaction]. | LitMetric
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[Effects of afobazole on the BDNF content in brain structures of inbred mice with different phenotypes of emotional stress reaction].

S B Seredin D S Melkumian E A Val'dman M A Iarkova T C Seredina M V Voronin A S Lapitskaia

Eksp Klin Farmakol

Published: September 2006

Changes in the BDNF content in brain structures--hippocampus, hypothalamus, striatum, and frontal cortex--were determined in mice of different emotional-stress reaction phenotypes, which were subjected to emotional stress and treated by the selective anxiolytic afobazole. The changes were different in BALB/c and C57BL/6 mice. Afobazole exhibited a significant protector action against a decrease in the brain BDNF level caused by emotional stress in BALB/c mice.

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