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Monoclonal antibodies in neuro-ophthalmology.
Saudi J Ophthalmol
March 2024
Department of Ophthalmology, Baylor College of Medicine, Houston, USA.
Neuro-ophthalmologic diseases include a broad range of disorders affecting the afferent and efferent visual pathways. Recently, monoclonal antibody (mAb) therapies have emerged as a promising targeted approach in the management of several of these complex conditions. Here, we describe the mechanism-specific applications and advancements in neuro-ophthalmologic mAb therapies.
View Article and Find Full Text PDFCase of Lemierre's Syndrome Presenting With Neuro-Ophthalmologic Complications That Worsened After Stopping Corticosteroids.
Cureus
February 2024
Department of Internal Medicine, Al-Ahli Hospital, Hebron, PSE.
Lemierre's syndrome (LS) is a rare disorder that manifests as septic internal jugular thrombophlebitis following a recent oropharyngeal infection. This article details a unique case of LS, where the patient presented to the emergency room with complaints of vomiting, headache, diplopia, and left eye pain. Due to a history of sore throat, headache, neck pain, fever, and nausea five days prior to admission, the patient was initially treated with amoxicillin/clavulanate for suspected tonsillitis.
View Article and Find Full Text PDFThe yield of neuroimaging in patients presenting to the emergency department with isolated neuro-ophthalmological complaints: A retrospective chart review.
Medicine (Baltimore)
January 2023
Ophthalmology Department, American University of Beirut Medical Center, Beirut, Lebanon.
Neuro-ophthalmological emergencies require prompt assessment and management to avoid vision or life-threatening sequelae. The decision to perform a neuroimaging procedure is based on the clinical judgment of the medical team, without defined indications. This study aims to identify presenting symptoms and physical exam findings associated with relative positive findings on neuroimaging studies.
View Article and Find Full Text PDFNeurological complications of giant cell arteritis: A study of 15 cases and a review of the literature.
J Fr Ophtalmol
March 2023
Neurology department, Mohamed VI hospital, Marrakesh, Morocco; Neuroscience research laboratory, Marrakech Medical school, Cadi Ayyad university, Marrakech, Morocco.
Background: Giant cell arteritis (GCA) is considered a neuro-ophthalmologic emergency. New-onset headache in patients aged 50 years and above with elevated erythrocyte sedimentation rate should prompt evaluation for GCA.
Material And Methods: Retrospective study of 15 patients presenting with GCA from 1991 to 2008 at the Mohamed V Military hospital at Rabat and Avicenne Military hospital of Marrakech.
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