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Machine learning based detection of T-wave alternans in real ambulatory conditions.
Comput Methods Programs Biomed
June 2024
Department of Teoría de la Señal y Comunicaciones, Universidad de Alcalá, Madrid, Spain. Electronic address:
Background And Objective: T-wave alternans (TWA) is a fluctuation in the repolarization morphology of the ECG. It is associated with cardiac instability and sudden cardiac death risk. Diverse methods have been proposed for TWA analysis.
View Article and Find Full Text PDFFocal atrial tachycardia mimicking catecholaminergic polymorphic ventricular tachycardia: a case report.
Eur Heart J Case Rep
November 2023
Department of Internal Medicine I, University of Wuerzburg, University Clinic, Oberdürrbacherstraße 6, Wuerzburg D-97080, Germany.
Background: In childhood and adolescence, cardiac arrhythmias are often benign in the absence of congenital heart defects. Nevertheless, life-threatening inherited arrhythmogenic syndromes can become clinically manifest in early childhood. As early symptoms may be similar in both conditions, thorough workup is fundamental to avoid delayed diagnosis and misdiagnosis.
View Article and Find Full Text PDFBiallelic truncating variants in children with titinopathy represent a recognizable condition with distinctive muscular and cardiac characteristics: a report on five patients.
Front Cardiovasc Med
July 2023
Laboratory of Medical Genetics, Translational Cytogenomics Research Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Article Synopsis
- This study investigates the connection between biallelic truncating variants and various musculoskeletal and cardiac disorders in children, emphasizing the limited understanding of cardiac issues associated with these variants in the pediatric population.
- Five pediatric patients with biallelic variants were reviewed, showing severe musculoskeletal problems (arthrogryposis multiplex) and significant cardiac issues, including dilated cardiomyopathy and congenital heart defects, with most patients diagnosed early in life.
- The findings suggest that biallelic variants should be considered in children displaying severe, early-onset dilated cardiomyopathy and skeletal abnormalities, as these conditions are often linked to end-stage heart failure, which may necessitate heart transplantation.
A case report of arrhythmogenic mitral valve disease: still a long way to go.
Eur Heart J Case Rep
October 2022
Cardiology Department, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Av. Prof. Dr. Reinaldo dos Santos, 2790-134 Carnaxide, Lisbon, Portugal.
Background: Mitral valve prolapse (MVP) is a common valvular heart disease and has often been associated with an increased risk of sudden cardiac death (SCD). This underlines the pressing need for the establishment of consistent tools for arrhythmic risk prediction.
Case Summary: A 73-year-old man with previous diagnosis of MVP was referred to the cardiology outpatient consult for a 1-month history of near-syncope and light-headedness.
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