We developed novel amino-modifying reagents, of which an amino group was connected with an aromatic residue by aliphatic linker. It was proved that the insertion of the aromatic residue could increase the reactivity of the amino group on oligonucleotides in comparison with conventional amino-modification.
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| http://dx.doi.org/10.1016/j.bmcl.2006.07.027 | DOI Listing |
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